Uploaded April 2026 | Updated September 2026, 2 weeks ago
Most people hear about kambo and think it’s reckless and dangerous, until they see what happens when it’s done right.
My understanding of kambo changed a lot through this conversation, especially after hearing how it’s been used not just as a traditional Amazonian medicine, but also as a tool for addressing complex health challenges. Caitlin Thompson (@MedicineFrogKambo) brings a rare blend of experience to this space, having served thousands of sessions while also approaching the work through a scientific lens rooted in neurobiology and research.
Her path into frog medicine came from navigating her own history with Lyme disease, lupus, and chronic illness, which gives real context to why she approaches this work with both precision and respect. We get into what kambo healing looks like in practice, including how dosage, safety, and nervous system state can completely change the outcome of a session.
There’s also a deeper conversation around why many people have overwhelming experiences, and how a more intentional, minimalist approach can unlock benefits around immune support, chronic illness recovery, and nervous system healing.
This is a grounded look at ancient tools meeting modern science, and what becomes possible when healing is approached with both rigor and humility.
Visit kambospecialist.com and use code LS10 for 10% off all online courses and ebooks.
THE LIFE STYLIST IS BROUGHT TO YOU BY:
LEELA QUANTUM | Go to lukestorey.com/leelaq and use code LUKE10 for 10% off your first order.
BIOPTIMIZERS | Visit bioptimizers.com/luke and use code LUKE15 to save 15% off sitewide.
PIQUE | Visit piquelife.com/luke to get 15% off for life when you subscribe.
REAL PROVISIONS | Visit RealProvisions.com/luke and use code LUKE to get a free bag of Venison Chips with your order.
You’ll learn:
[00:00] Introduction
[10:06] Frog medicine 101: what it is, what it does, and how it's collected
[15:32] Nobody actually knows who discovered kambo first
[27:52] Why doing more kambo doesn't mean getting more out of it
[40:05] How Caitlin's personal relationship with kambo has evolved over a decade
[52:41] What's happening to frog populations and the communities behind the medicine
[01:05:54] Mixing kambo with psychedelics is riskier than most people think
[01:13:58] Who should and shouldn't take kambo, and what it can do for addiction
[01:36:21] Treating Lyme without addressing trauma may be why people don't get better
[01:50:31] Is it the substance that's intelligent or something working through it?
Resources mentioned:
Phyllomedusa bicolor | bit.ly/phyllomedusa_bicolor
Matsés | bit.ly/matsés-A9s
Sananga | bit.ly/sananga-tabundulata
Rapé | bit.ly/rapé-nicorustica
Read: Thompson et al, Use of Phyllomedusa bicolour secretion during kambô ritual: observational responses, dosage, and risk of adverse events | bit.ly/phyllo-bicolour-sec
Read: Thompson & Williams, Review of the physiological effects of Phyllomedusa bicolor skin secretion peptides on humans receiving Kambô | bit.ly/review-physioeff-bs
Institute of Kambo Advancement and Preservation | kamboinstitute.org
Peter Gorman | sapoinmysoul.com
Read: WTFrog Is Kambo and Am I Ready: A Practical Guide to Understanding the Experience, Staying Safe, and Evaluating If Kambo Is Right For You | bit.ly/wtfrog-is-kambo-and-am-i-ready
Todd Shipman | modernkambo.com
Full show notes at lukestorey.com/kambo
Find more from Caitlin:
Medicine Frog Kambo | medicinefrogkambo.com | instagram.com/medicinefrogkambo | facebook.com/medicinefrogkambo | youtube.com/@UCCw1Ou4k63vTVg-TUUeHetw
Medicine Frog Kambo Practitioner Training | kambospecialist.com
Institute of Kambo Advancement and Preservation (IKAP) | kamboinstitute.org
Kambocon | kambocon.com
Find more from Luke:
Luke Storey | instagram.com/lukestorey | facebook.com/lukecstorey | https://x.com/MrLukeStorey | youtube.com/lukestorey | linkedin.com/in/mrlukestorey
Most people hear about kambo and think it’s reckless and dangerous, until they see what happens when it’s done right.
My understanding of kambo changed a lot through this conversation, especially after hearing how it’s been used not just as a traditional Amazonian medicine, but also as a tool for addressing complex health challenges. Caitlin Thompson (@MedicineFrogKambo) brings a rare blend of experience to this space, having served thousands of sessions while also approaching the work through a scientific lens rooted in neurobiology and research.
Her path into frog medicine came from navigating her own history with Lyme disease, lupus, and chronic illness, which gives real context to why she approaches this work with both precision and respect. We get into what kambo healing looks like in practice, including how dosage, safety, and nervous system state can completely change the outcome of a session.
There’s also a deeper conversation around why many people have overwhelming experiences, and how a more intentional, minimalist approach can unlock benefits around immune support, chronic illness recovery, and nervous system healing.
This is a grounded look at ancient tools meeting modern science, and what becomes possible when healing is approached with both rigor and humility.
Visit kambospecialist.com and use code LS10 for 10% off all online courses and ebooks.
THE LIFE STYLIST IS BROUGHT TO YOU BY:
LEELA QUANTUM | Go to lukestorey.com/leelaq and use code LUKE10 for 10% off your first order.
BIOPTIMIZERS | Visit bioptimizers.com/luke and use code LUKE15 to save 15% off sitewide.
PIQUE | Visit piquelife.com/luke to get 15% off for life when you subscribe.
REAL PROVISIONS | Visit RealProvisions.com/luke and use code LUKE to get a free bag of Venison Chips with your order.
You’ll learn:
[00:00] Introduction
[10:06] Frog medicine 101: what it is, what it does, and how it's collected
[15:32] Nobody actually knows who discovered kambo first
[27:52] Why doing more kambo doesn't mean getting more out of it
[40:05] How Caitlin's personal relationship with kambo has evolved over a decade
[52:41] What's happening to frog populations and the communities behind the medicine
[01:05:54] Mixing kambo with psychedelics is riskier than most people think
[01:13:58] Who should and shouldn't take kambo, and what it can do for addiction
[01:36:21] Treating Lyme without addressing trauma may be why people don't get better
[01:50:31] Is it the substance that's intelligent or something working through it?
Resources mentioned:
Phyllomedusa bicolor | bit.ly/phyllomedusa_bicolor
Matsés | bit.ly/matsés-A9s
Sananga | bit.ly/sananga-tabundulata
Rapé | bit.ly/rapé-nicorustica
Read: Thompson et al, Use of Phyllomedusa bicolour secretion during kambô ritual: observational responses, dosage, and risk of adverse events | bit.ly/phyllo-bicolour-sec
Read: Thompson & Williams, Review of the physiological effects of Phyllomedusa bicolor skin secretion peptides on humans receiving Kambô | bit.ly/review-physioeff-bs
Institute of Kambo Advancement and Preservation | kamboinstitute.org
Peter Gorman | sapoinmysoul.com
Read: WTFrog Is Kambo and Am I Ready: A Practical Guide to Understanding the Experience, Staying Safe, and Evaluating If Kambo Is Right For You | bit.ly/wtfrog-is-kambo-and-am-i-ready
Todd Shipman | modernkambo.com
Full show notes at lukestorey.com/kambo
Find more from Caitlin:
Medicine Frog Kambo | medicinefrogkambo.com | instagram.com/medicinefrogkambo | facebook.com/medicinefrogkambo | youtube.com/@UCCw1Ou4k63vTVg-TUUeHetw
Medicine Frog Kambo Practitioner Training | kambospecialist.com
Institute of Kambo Advancement and Preservation (IKAP) | kamboinstitute.org
Kambocon | kambocon.com
Find more from Luke:
Luke Storey | instagram.com/lukestorey | facebook.com/lukecstorey | https://x.com/MrLukeStorey | youtube.com/lukestorey | linkedin.com/in/mrlukestorey
