Uploaded March 2025 | Updated September 2026, 2 days ago
Moyamoya disease is a rare neurovascular condition that can affect both children and adults and is caused by progressive narrowing or blockage of the major blood vessels supplying the brain.
The result is a lack of necessary blood flow to the brain, which can cause stroke, mini-stroke (TIA – transient ischemic attack) or bleeding into the brain. Numerous tiny vessels develop around the blockage in an attempt to compensate for the lowered blood flow, leading to a smoky appearance of these vessels on imaging. This smoky appearance is what gives the disease its name, as “moyamoya” means puff of smoke in Japanese.
Aditya (Adi) Iyer MD, MS, is a fellowship-trained neurosurgeon with a focus on vascular diseases of the brain and spine at Pacific Neuroscience Institute. As one of California’s few dual-trained neurosurgeons, Dr. Iyer is able to offer both minimally invasive open surgical techniques as well as incisionless catheter based procedures to treat patients with strokes, aneurysms, AVMs, tumors and pain.
Moyamoya disease is a rare neurovascular condition that can affect both children and adults and is caused by progressive narrowing or blockage of the major blood vessels supplying the brain.
The result is a lack of necessary blood flow to the brain, which can cause stroke, mini-stroke (TIA – transient ischemic attack) or bleeding into the brain. Numerous tiny vessels develop around the blockage in an attempt to compensate for the lowered blood flow, leading to a smoky appearance of these vessels on imaging. This smoky appearance is what gives the disease its name, as “moyamoya” means puff of smoke in Japanese.
Aditya (Adi) Iyer MD, MS, is a fellowship-trained neurosurgeon with a focus on vascular diseases of the brain and spine at Pacific Neuroscience Institute. As one of California’s few dual-trained neurosurgeons, Dr. Iyer is able to offer both minimally invasive open surgical techniques as well as incisionless catheter based procedures to treat patients with strokes, aneurysms, AVMs, tumors and pain.
