Uploaded June 2026 | Updated September 2026, 2 weeks ago
Watch episodes & bonus content ad-free on bialikbreakdown.substack.com
Dr. Rick Doblin (founder and president of the Multidisciplinary Association for Psychedelic Studies, and one of the most influential figures in psychedelic science) returns to Mayim Bialik's Breakdown for one of the most controversial and eye-opening conversations on psychedelics we've had yet.
From the shocking experiment where scientists gave MDMA to an octopus, to why ibogaine may be the most powerful AND dangerous psychedelic ever studied, this episode explores the future of psychedelic therapy, trauma healing, addiction recovery, policy reform, and human consciousness itself.
We break down Trump’s new executive order accelerating psychedelic research and what it could mean for the future legalization of psychedelic-assisted therapy in America. Dr. Doblin explains why veterans suffering from PTSD and disabilities have become central to bipartisan support for psychedelics, and why this issue is now reshaping politics on both sides of the aisle.
We also dive deep into ibogaine: its mysterious origins, its ability to help reset opioid addiction, its connection to ancestral memory and intergenerational trauma, why it carries serious risks, and why Dr. Doblin still believes its benefits may outweigh the dangers. He also shares his own profound ibogaine experience that helped him confront perfectionism and his fear of death.
Dr. Doblin discusses:
- How psychedelics help people integrate trauma
- Why psychedelics are generally considered non-addictive
- Difference between recreational vs therapeutic psychedelic use
- Why psychedelic treatment should be customized to each patient
- Importance of integration, peer support, and paying attention to dreams after treatment
- Measures of success in MDMA-assisted couples therapy
- Origins of the opioid epidemic
- "Psychedelic churches": How organizations are openly operating under the umbrella of religion
- Capitalism vs democratizing the benefits of psychedelic medicine
- How a better psychedelic therapy model could be built
- Why transparency is critical for science-backed drug policy reform
- When psychedelics may realistically enter the open market
- Dr. Doblin’s long-term vision for a psychedelic-informed public
As psychedelic research rapidly expands worldwide, this conversation explores the science, politics, risks, ethics, and revolutionary potential behind one of the fastest-growing movements in mental health and medicine!
DISCLAIMER: MBB is not providing medical or legal advice. Listeners should speak to their doctor before engaging in any course of psychedelic protocols. Psychedelics are still illegal in many places - MBB is not encouraging engaging in illegal substance use, but simply sharing the latest scientific insights from our guests.
---
00:00 - Intro
04:04 - Why Psychedelic Research is Currently Flourishing
08:41 - Why Veterans are Crucial to Bipartisan Support
11:30 - Ibogaine Connection to Ancestral Memories
23:43 - Ibogaine Risks, Safety, & Studies
31:47 - Origins of the Opioid Crisis
50:43 - MDMA Goes Mainstream
52:29 - Owning Your Shadow
1:05:39 - Importance of Integration
1:10:09 - What Happens When You Give MDMA to an Octopus?
1:25:03 - Therapy Vs Profit Motives
1:30:22 - Why Peer Support Matters
1:31:17 - MDMA Couples Therapy
1:35:32 - Bipartisan Funding Bridges
1:40:32 - Executive Order Fast Track
1:47:37 - Psychedelic Churches Rise
---
Rula patients typically pay $15 per session when using insurance. Connect with quality therapists and mental health experts who specialize in you at rula.com/break
#rulapod
Text BREAKDOWN to 64000 to get 20% off all IQBAR products, plus FREE shipping. Message and data rates may apply.
Head to Superpower.com and use code BREAK at checkout for $20 off your membership. Unlock your new health intelligence. 100+ biomarkers. Every year. Detect early signs of 1,000+ conditions. #superpowerpod
---
Website: https://www.bialikbreakdown.com
Spotify: open.spotify.com/show/6TgOe2poCdpZtQwKetQmU1
Apple Podcasts: podcasts.apple.com/us/podcast/mayim-bialiks-breakdown/id1546456269
Merch: shop.bialikbreakdown.com
IG:: instagram.com/bialikbreakdown
Find Mayim:
mayimbialik.substack.com
facebook.com/MissMayim/
twitter.com/MissMayim/
instagram.com/MissMayim/
tiktok.com/@mayimbialik
Find Dr. Rick Doblin
Twitter: twitter.com/RickDoblin
Instagram: instagram.com/rickdoblinphd
Learn more about MAPS & their research: maps.org
To learn more about the world’s largest psychedelic conference, Psychedelic Science, taking place in Denver, CO next year, visit: virtualtrip.maps.org
If interested in partnerships please contact mbb.sponsor@impacttheory.com
Theme Song Written, Produced, and Performed by Ed Robertson. Mixed by Kenny Luong.
#psychedelictherapy
Watch episodes & bonus content ad-free on bialikbreakdown.substack.com
Dr. Rick Doblin (founder and president of the Multidisciplinary Association for Psychedelic Studies, and one of the most influential figures in psychedelic science) returns to Mayim Bialik's Breakdown for one of the most controversial and eye-opening conversations on psychedelics we've had yet.
From the shocking experiment where scientists gave MDMA to an octopus, to why ibogaine may be the most powerful AND dangerous psychedelic ever studied, this episode explores the future of psychedelic therapy, trauma healing, addiction recovery, policy reform, and human consciousness itself.
We break down Trump’s new executive order accelerating psychedelic research and what it could mean for the future legalization of psychedelic-assisted therapy in America. Dr. Doblin explains why veterans suffering from PTSD and disabilities have become central to bipartisan support for psychedelics, and why this issue is now reshaping politics on both sides of the aisle.
We also dive deep into ibogaine: its mysterious origins, its ability to help reset opioid addiction, its connection to ancestral memory and intergenerational trauma, why it carries serious risks, and why Dr. Doblin still believes its benefits may outweigh the dangers. He also shares his own profound ibogaine experience that helped him confront perfectionism and his fear of death.
Dr. Doblin discusses:
- How psychedelics help people integrate trauma
- Why psychedelics are generally considered non-addictive
- Difference between recreational vs therapeutic psychedelic use
- Why psychedelic treatment should be customized to each patient
- Importance of integration, peer support, and paying attention to dreams after treatment
- Measures of success in MDMA-assisted couples therapy
- Origins of the opioid epidemic
- "Psychedelic churches": How organizations are openly operating under the umbrella of religion
- Capitalism vs democratizing the benefits of psychedelic medicine
- How a better psychedelic therapy model could be built
- Why transparency is critical for science-backed drug policy reform
- When psychedelics may realistically enter the open market
- Dr. Doblin’s long-term vision for a psychedelic-informed public
As psychedelic research rapidly expands worldwide, this conversation explores the science, politics, risks, ethics, and revolutionary potential behind one of the fastest-growing movements in mental health and medicine!
DISCLAIMER: MBB is not providing medical or legal advice. Listeners should speak to their doctor before engaging in any course of psychedelic protocols. Psychedelics are still illegal in many places - MBB is not encouraging engaging in illegal substance use, but simply sharing the latest scientific insights from our guests.
---
00:00 - Intro
04:04 - Why Psychedelic Research is Currently Flourishing
08:41 - Why Veterans are Crucial to Bipartisan Support
11:30 - Ibogaine Connection to Ancestral Memories
23:43 - Ibogaine Risks, Safety, & Studies
31:47 - Origins of the Opioid Crisis
50:43 - MDMA Goes Mainstream
52:29 - Owning Your Shadow
1:05:39 - Importance of Integration
1:10:09 - What Happens When You Give MDMA to an Octopus?
1:25:03 - Therapy Vs Profit Motives
1:30:22 - Why Peer Support Matters
1:31:17 - MDMA Couples Therapy
1:35:32 - Bipartisan Funding Bridges
1:40:32 - Executive Order Fast Track
1:47:37 - Psychedelic Churches Rise
---
Rula patients typically pay $15 per session when using insurance. Connect with quality therapists and mental health experts who specialize in you at rula.com/break
#rulapod
Text BREAKDOWN to 64000 to get 20% off all IQBAR products, plus FREE shipping. Message and data rates may apply.
Head to Superpower.com and use code BREAK at checkout for $20 off your membership. Unlock your new health intelligence. 100+ biomarkers. Every year. Detect early signs of 1,000+ conditions. #superpowerpod
---
Website: https://www.bialikbreakdown.com
Spotify: open.spotify.com/show/6TgOe2poCdpZtQwKetQmU1
Apple Podcasts: podcasts.apple.com/us/podcast/mayim-bialiks-breakdown/id1546456269
Merch: shop.bialikbreakdown.com
IG:: instagram.com/bialikbreakdown
Find Mayim:
mayimbialik.substack.com
facebook.com/MissMayim/
twitter.com/MissMayim/
instagram.com/MissMayim/
tiktok.com/@mayimbialik
Find Dr. Rick Doblin
Twitter: twitter.com/RickDoblin
Instagram: instagram.com/rickdoblinphd
Learn more about MAPS & their research: maps.org
To learn more about the world’s largest psychedelic conference, Psychedelic Science, taking place in Denver, CO next year, visit: virtualtrip.maps.org
If interested in partnerships please contact mbb.sponsor@impacttheory.com
Theme Song Written, Produced, and Performed by Ed Robertson. Mixed by Kenny Luong.
#psychedelictherapy
