The New “Endemic Phase” and a Vaccine Update @UCSFDepartmentofMedicine
The New “Endemic Phase” and a Vaccine Update  @UCSFDepartmentofMedicine
Uploaded March 2022 | Updated September 2026, 1 week ago
In this Covid Grand Rounds, we’ll begin with a pandemic update from Monica Gandhi and Peter Chin-Hong. We’ll discuss the CDC’s new mask guidance, the Omicron sub-variant, infection-related and hybrid immunity, and what it means to enter the “endemic phase.”

In the second segment, Bonnie Maldonado of Stanford University will give us a vaccine update, including the evidence of waning immunity after vaccination, the prospects for a second booster, the state of vaccines for children, and new vaccine candidates, including Omicron-specific boosters. The session will be moderated by Bob Wachter.

Speakers:
Peter Chin-Hong, MD, Professor of Medicine, Division of Infectious Diseases at UCSF Health; Associate Dean for Regional Campuses, UCSF School of Medicine

Monica Gandhi, MD, MPH, Professor of Medicine; Associate Chief of Division of HIV, Infectious Diseases, and Global Medicine at ZSFG; Director of the UCSF-Gladstone Center for AIDS Research; Medical Director of the HIV Clinic, Ward 86, ZSFG

Yvonne Maldonado, MD, Professor and Chief of the Division of Infectious Diseases, Dept. of Pediatrics at Stanford University School of Medicine; Senior Associate Dean for Faculty Development and Diversity at the Stanford School of Medicine

Note: Closed captions will be available within 48-72 hours after posting.

Program
Bob Wachter: Introduction
00:02:46-00:29:43 – Pandemic update with Monica Gandhi (Professor of Medicine; Associate Chief of Division of HIV, Infectious Diseases, and Global Medicine at ZSFG; Director of the UCSF-Gladstone Center for AIDS Research; Medical Director of the HIV Clinic, Ward 86, ZSFG)
and Peter Chin-Hong (Professor of Medicine, Division of Infectious Diseases at UCSF Health; Associate Dean for Regional Campuses, UCSF School of Medicine)
00:29:45-01:03:05 – Vaccine update with Yvonne Maldonado (Professor and Chief of the Division of Infectious Diseases, Dept. of Pediatrics at Stanford University School of Medicine; Senior Associate Dean for Faculty Development and Diversity at the Stanford School of Medicine)
Bob Wachter: Closing

See previous Medical Grand Rounds:
• February 24: Clinical Problem Solving with Lisa Winston
youtu.be/C0ojeYm7c2w
• February 10: The 24th Annual Reza Gandjei Memorial Lecture: A Fireside Chat with Megan Ranney
youtube.com/watch?v=KSml7D5fIK4
• February 3: The Downslope of the Omicron Surge, and What to Do as We Turn the Corner
youtube.com/watch?v=JKaPbBQNneE
• January 27: Rebuilding What We've Lost in Covid: A Perspective from the ICU
youtube.com/watch?v=EgIXrcKRWYw&t=1s

See all UCSF Covid-19 grand rounds, which have been viewed over 3M times, here: https://medicine.ucsf.edu/covid-19-news-coverage
The New “Endemic Phase” and a Vaccine UpdateHospital-Based Oncology for the InternistUpdates in Addiction Medicine: Overdose Reduction, Equity, and Innovations in Care DeliveryInnovations and Controversy: Updates in GeriatricsAn Immunotherapy Renaissance in Hepatobiliary CancersThe Final Covid-19 Grand Rounds: What Have We Learned?The Cough Wont Stop: Updates in Bronchiectasis, from Airways to BugsFinding Your North Star in Medical EducationUpdated Thyroid Cancer Guidelines: Personalized Approaches for Optimized CareViral Summer: Navigating the Evolving Landscape of COVID-19, H5N1 Influenza, and MeaslesUpdates in Large Vessel VasculitisThe 28th Annual Reza Gandjei Lecture — Primary Care’s Moment: Crisis and Opportunity
UCSF Department of Medicine |

The New “Endemic Phase” and a Vaccine Update

SHARE TO X SHARE TO REDDIT SHARE TO FACEBOOK WALLPAPER