Uploaded December 2022 | Updated September 2026, 2 days ago
Has modern medicine and family planning led to a dangerous accumulation of deleterious mutations in humans that will eventually lead to our extinction? Answer: No.
In this video, I provide the history of the concept of genetic load (including it's troubling eugenics past), give the basic population genetic theory as applied to functionality in the human genome, and explain the context dependence of mutational fitness effects.
PS: I say I'm going to give Roth & Wakeley the last word and then just keep talking lol....
Has modern medicine and family planning led to a dangerous accumulation of deleterious mutations in humans that will eventually lead to our extinction? Answer: No.
In this video, I provide the history of the concept of genetic load (including it's troubling eugenics past), give the basic population genetic theory as applied to functionality in the human genome, and explain the context dependence of mutational fitness effects.
PS: I say I'm going to give Roth & Wakeley the last word and then just keep talking lol....










