Uploaded July 2026 | Updated September 2026, 2 weeks ago
Your bloodwork can come back “normal” while cortisol, nutrient deficiencies, gut dysfunction and hidden immune triggers continue driving exhaustion, weight-loss resistance and hormonal decline. Dr. Stephen Cabral joins Dr. Josh Axe to explain why treating an isolated diagnosis may fail when the real problem is an interconnected biological pattern that standard testing never uncovered.
Uncover what’s really going on in your body with advanced biomarker testing for hormones, thyroid, and metabolism— plus a 1-hour consultation with a Senior Health Advisor! → mybloodwork.com
Thank you to our sponsors!
Sunlighten Sauna: get.sunlighten.com/axepodcast
Manukora Manuka Honey: manukora.com/axe
Caraway Home: carawayhome.com/drjoshaxe (Use code DRJOSHAXE) for an exclusive discount
Watch The Dr. Josh Axe Show every Monday & Thursday on YouTube: youtube.com/@drjoshaxe?sub_confirmation=1
🎧 Early Access!
Our listeners enjoy every episode before anyone else! Tune in below and join our exclusive group of listeners →
Spotify: bit.ly/DrJoshAxeSpotify
Apple Podcast: apple.co/3JDvWcS
Pre-order my NEW BOOK, Heal Your Cells → bit.ly/3QJBcQ5
Watch my free training on how to naturally balance your blood sugar and reverse your symptoms → DrAxeDiabetesClass.com
Discover practical steps you can take today to start healing your thyroid naturally → DrAxeThyroidClass.com
If you’re ready to start feeling like yourself again and balance your hormones, take my free class → DrAxeHormoneClass.com
CONNECT WITH DR. JOSH AXE
Instagram → instagram.com/drjoshaxe
Facebook → facebook.com/DrJoshAxe
TikTok → tiktok.com/@thedrjoshaxeshow
X → https://x.com/drjoshaxe/
LinkedIn → linkedin.com/in/joshaxe
Website → thehealthinstitute.com
Sign up for my newsletter → bit.ly/4oE9Jf3
Ask Dr. Axe → speakpipe.com/drjoshaxe
CONNECT WITH GUEST
Instagram → instagram.com/stephencabral
Facebook → facebook.com/drstephencabral
YouTube → youtube.com/stephencabral
TikTok → instagram.com/stephencabral
X → https://x.com/stephencabral
Website → stephencabral.com
00:00 — Why “Normal” Bloodwork Can Miss the Root Cause
01:46 — Dr. Stephen Cabral on Personalized Root-Cause Medicine
03:28 — How Addison’s Disease, Autoimmunity and Diabetes Became Connected
07:14 — The Cortisol Connection to Thyroid, Testosterone and Blood Sugar
11:11 — How Chronic Stress Disrupts the Entire Hormonal System
14:58 — At-Home Hormone, Thyroid and Metabolism Testing
16:44 — The Three Foundations for Restoring Cortisol Rhythm
20:35 — Why Sleep May Matter More Than Diet
23:36 — When Cold Plunging Can Make Fatigue and Burnout Worse
27:09 — Why 100 Blood Markers May Still Tell You Nothing
30:47 — The Micronutrients That Transformed Dr. Axe’s Energy
33:58 — Dr. Cabral’s “Big Five” Functional Lab Tests
38:39 — Why the Same Diet or Hashimoto’s Protocol Produces Different Results
40:41 — Leaky Gut, Molecular Mimicry and Autoimmune Disease
45:56 — Cortisol, Progesterone and the Root of Menopause Symptoms
49:27 — DHEA, Adaptogens and Restoring Hormone Balance
51:04 — Is Melatonin Safe? Dosage, Sleep and Cancer Research
55:03 — Does Melatonin Shut Down Your Natural Production?
56:25 — The Hidden Side Effects of Testosterone Replacement Therapy
01:00:20 — The Root Causes of Low Testosterone in Younger Men
01:03:55 — How to Identify Your Personal Biological Blueprint
01:06:16 — The Diet and Exercise Combination That May Harm Fertility
DISCLAIMER
This content is strictly the opinion of Dr. Josh Axe and is for informational and educational purposes only. It is not intended to provide medical advice or to take the place of medical advice or treatment from a personal physician. All viewers of this content are advised to consult their doctors or qualified health professionals regarding specific health questions. Neither Dr. Axe nor the publisher of this content takes responsibility for possible health consequences of any person or persons reading or following the information in this educational content. All viewers of this content, especially those taking prescription or over-the-counter medications, should consult their physicians before beginning any nutrition, supplement or lifestyle program.
MB01ECARA9TSXF7
Your bloodwork can come back “normal” while cortisol, nutrient deficiencies, gut dysfunction and hidden immune triggers continue driving exhaustion, weight-loss resistance and hormonal decline. Dr. Stephen Cabral joins Dr. Josh Axe to explain why treating an isolated diagnosis may fail when the real problem is an interconnected biological pattern that standard testing never uncovered.
Uncover what’s really going on in your body with advanced biomarker testing for hormones, thyroid, and metabolism— plus a 1-hour consultation with a Senior Health Advisor! → mybloodwork.com
Thank you to our sponsors!
Sunlighten Sauna: get.sunlighten.com/axepodcast
Manukora Manuka Honey: manukora.com/axe
Caraway Home: carawayhome.com/drjoshaxe (Use code DRJOSHAXE) for an exclusive discount
Watch The Dr. Josh Axe Show every Monday & Thursday on YouTube: youtube.com/@drjoshaxe?sub_confirmation=1
🎧 Early Access!
Our listeners enjoy every episode before anyone else! Tune in below and join our exclusive group of listeners →
Spotify: bit.ly/DrJoshAxeSpotify
Apple Podcast: apple.co/3JDvWcS
Pre-order my NEW BOOK, Heal Your Cells → bit.ly/3QJBcQ5
Watch my free training on how to naturally balance your blood sugar and reverse your symptoms → DrAxeDiabetesClass.com
Discover practical steps you can take today to start healing your thyroid naturally → DrAxeThyroidClass.com
If you’re ready to start feeling like yourself again and balance your hormones, take my free class → DrAxeHormoneClass.com
CONNECT WITH DR. JOSH AXE
Instagram → instagram.com/drjoshaxe
Facebook → facebook.com/DrJoshAxe
TikTok → tiktok.com/@thedrjoshaxeshow
X → https://x.com/drjoshaxe/
LinkedIn → linkedin.com/in/joshaxe
Website → thehealthinstitute.com
Sign up for my newsletter → bit.ly/4oE9Jf3
Ask Dr. Axe → speakpipe.com/drjoshaxe
CONNECT WITH GUEST
Instagram → instagram.com/stephencabral
Facebook → facebook.com/drstephencabral
YouTube → youtube.com/stephencabral
TikTok → instagram.com/stephencabral
X → https://x.com/stephencabral
Website → stephencabral.com
00:00 — Why “Normal” Bloodwork Can Miss the Root Cause
01:46 — Dr. Stephen Cabral on Personalized Root-Cause Medicine
03:28 — How Addison’s Disease, Autoimmunity and Diabetes Became Connected
07:14 — The Cortisol Connection to Thyroid, Testosterone and Blood Sugar
11:11 — How Chronic Stress Disrupts the Entire Hormonal System
14:58 — At-Home Hormone, Thyroid and Metabolism Testing
16:44 — The Three Foundations for Restoring Cortisol Rhythm
20:35 — Why Sleep May Matter More Than Diet
23:36 — When Cold Plunging Can Make Fatigue and Burnout Worse
27:09 — Why 100 Blood Markers May Still Tell You Nothing
30:47 — The Micronutrients That Transformed Dr. Axe’s Energy
33:58 — Dr. Cabral’s “Big Five” Functional Lab Tests
38:39 — Why the Same Diet or Hashimoto’s Protocol Produces Different Results
40:41 — Leaky Gut, Molecular Mimicry and Autoimmune Disease
45:56 — Cortisol, Progesterone and the Root of Menopause Symptoms
49:27 — DHEA, Adaptogens and Restoring Hormone Balance
51:04 — Is Melatonin Safe? Dosage, Sleep and Cancer Research
55:03 — Does Melatonin Shut Down Your Natural Production?
56:25 — The Hidden Side Effects of Testosterone Replacement Therapy
01:00:20 — The Root Causes of Low Testosterone in Younger Men
01:03:55 — How to Identify Your Personal Biological Blueprint
01:06:16 — The Diet and Exercise Combination That May Harm Fertility
DISCLAIMER
This content is strictly the opinion of Dr. Josh Axe and is for informational and educational purposes only. It is not intended to provide medical advice or to take the place of medical advice or treatment from a personal physician. All viewers of this content are advised to consult their doctors or qualified health professionals regarding specific health questions. Neither Dr. Axe nor the publisher of this content takes responsibility for possible health consequences of any person or persons reading or following the information in this educational content. All viewers of this content, especially those taking prescription or over-the-counter medications, should consult their physicians before beginning any nutrition, supplement or lifestyle program.
MB01ECARA9TSXF7
