Uploaded March 2023 | Updated September 2026, 12 hours ago
We now understand the many causes of the obesity crisis better than ever. Does that bring hope to the overweight or despair that we'll all succumb?
0:00 Dude looks like a lady
0:49 Kevin Hall paper
1:59 BMI is heritable
3:11 NIH facilities
5:02 The test diets
6:32 NOVA ranking system for foods
9:16 Unlimited food
9:58 The body's setpoint
10:52 The Protein leverage hypothesis
14:10 It's the processing
17:18 Calorie density
18:08 New model of palatability
21:58 BMI is heritable
24:35 Is it sugar?
VIDEOS REFERENCED:
Tera Fazzino, a classification system for palatability of ultra processed food
youtu.be/CKaMVTZUG-E
Carlos Monteiro on the Dangers of Ultra-processed Foods
youtu.be/b4KXe83fz5A
Evil tricks the food companies play: why we can't lose weight and get healthy.
youtu.be/ADGWIKG4RVQ
Food, Energy, and Obesity - Kevin Hall, NIH Physicist
youtu.be/t9UHLwQaf5c
PAPERS CITED:
Ultra-Processed Diets Cause Excess Calorie Intake and Weight Gain: An Inpatient Randomized Controlled Trial of Ad Libitum Food Intake, by Kevin Hall
cell.com/cell-metabolism/fulltext/S1550-4131(19)30248-7
Hyper-Palatable Foods: Development of a Quantitative
Definition and Application to the US Food System
Database, by Tera Fazzino
https://kuscholarworks.ku.edu/bitstream/handle/1808/29721/Fazzino_et_al-2019-Obesity.pdf
ULTRA-PROCESSED FOODS: NOVA CLASSIFICATION
regulatory.mxns.com/en/ultra-processed-foods-nova-classification
Ad libitum meal energy intake is positively influenced by energy density, eating rate and hyper-palatable food across four dietary patterns, by Tera Fazzino and Kevin Hall
nature.com/articles/s43016-022-00688-4
The potential role of protein leverage in the US obesity epidemic
ncbi.nlm.nih.gov/pmc/articles/PMC7147114
Protein status elicits compensatory changes in food intake and food preferences
academic.oup.com/ajcn/article/95/1/32/4576667
Obesity: the protein leverage hypothesis by S J Simpson, D Raubenheimer
pubmed.ncbi.nlm.nih.gov/15836464
The Human Energy Crisis: Kevin Hall applies a physicist’s view of energy to the human body.
irp.nih.gov/our-research/research-in-action/the-human-energy-crisis
Effect of a plant-based, low-fat diet versus an animal-based, ketogenic diet on ad libitum energy intake, by Kevin Hall
https://sci-hub.se/10.1038/s41591-020-01209-1
What I learned about weight loss from spending a day inside a metabolic chamber: One of science’s best tools for understanding obesity is debunking myths about metabolism.
vox.com/2018/9/4/17486110/metabolism-diet-fast-weight-loss
BOOKS REFERENCED
The Dorito Effect: The Surprising New Truth About Food and Flavor, by Mark Schatzker
amazon.com/The-Dorito-Effect-Mark-Schatzker-audiobook/dp/B00WXS745G/ref=sr_1_1
Salt Sugar Fat: How the Food Giants Hooked Us, by Michael Moss
amazon.com/Salt-Sugar-Fat-Michael-Moss-audiobook/dp/B00B4G0MMK/ref=sr_1_1
The Hungry Brain: Outsmarting the Instincts That Make Us Overeat, by Stephan Guyenet
amazon.com/The-Hungry-Brain-audiobook/dp/B01MY2QWYM/ref=sr_1_1
Nature Wants Us to Be Fat: The Surprising Science Behind Why We Gain Weight and How We Can Prevent--and Reverse--It, by Richard Johnson
amazon.com/Nature-Wants-Fat-Prevent-Reverse/dp/1637740344
Metabolical: The Lure and the Lies of Processed Food, Nutrition, and Modern Medicine, by Robert Lustig
amazon.com/Metabolical-Processed-Nutrition-Modern-Medicine/dp/B08LP21JLQ/ref=sr_1_1
The Nature of Nutrition: A Unifying Framework from Animal Adaptation to Human Obesity by Stephen J. Simpson, David Raubenheimer
amazon.com/Nature-Nutrition-Unifying-Framework-Adaptation-ebook/dp/B007BOKOFO/ref=sr_1_1
We now understand the many causes of the obesity crisis better than ever. Does that bring hope to the overweight or despair that we'll all succumb?
0:00 Dude looks like a lady
0:49 Kevin Hall paper
1:59 BMI is heritable
3:11 NIH facilities
5:02 The test diets
6:32 NOVA ranking system for foods
9:16 Unlimited food
9:58 The body's setpoint
10:52 The Protein leverage hypothesis
14:10 It's the processing
17:18 Calorie density
18:08 New model of palatability
21:58 BMI is heritable
24:35 Is it sugar?
VIDEOS REFERENCED:
Tera Fazzino, a classification system for palatability of ultra processed food
youtu.be/CKaMVTZUG-E
Carlos Monteiro on the Dangers of Ultra-processed Foods
youtu.be/b4KXe83fz5A
Evil tricks the food companies play: why we can't lose weight and get healthy.
youtu.be/ADGWIKG4RVQ
Food, Energy, and Obesity - Kevin Hall, NIH Physicist
youtu.be/t9UHLwQaf5c
PAPERS CITED:
Ultra-Processed Diets Cause Excess Calorie Intake and Weight Gain: An Inpatient Randomized Controlled Trial of Ad Libitum Food Intake, by Kevin Hall
cell.com/cell-metabolism/fulltext/S1550-4131(19)30248-7
Hyper-Palatable Foods: Development of a Quantitative
Definition and Application to the US Food System
Database, by Tera Fazzino
https://kuscholarworks.ku.edu/bitstream/handle/1808/29721/Fazzino_et_al-2019-Obesity.pdf
ULTRA-PROCESSED FOODS: NOVA CLASSIFICATION
regulatory.mxns.com/en/ultra-processed-foods-nova-classification
Ad libitum meal energy intake is positively influenced by energy density, eating rate and hyper-palatable food across four dietary patterns, by Tera Fazzino and Kevin Hall
nature.com/articles/s43016-022-00688-4
The potential role of protein leverage in the US obesity epidemic
ncbi.nlm.nih.gov/pmc/articles/PMC7147114
Protein status elicits compensatory changes in food intake and food preferences
academic.oup.com/ajcn/article/95/1/32/4576667
Obesity: the protein leverage hypothesis by S J Simpson, D Raubenheimer
pubmed.ncbi.nlm.nih.gov/15836464
The Human Energy Crisis: Kevin Hall applies a physicist’s view of energy to the human body.
irp.nih.gov/our-research/research-in-action/the-human-energy-crisis
Effect of a plant-based, low-fat diet versus an animal-based, ketogenic diet on ad libitum energy intake, by Kevin Hall
https://sci-hub.se/10.1038/s41591-020-01209-1
What I learned about weight loss from spending a day inside a metabolic chamber: One of science’s best tools for understanding obesity is debunking myths about metabolism.
vox.com/2018/9/4/17486110/metabolism-diet-fast-weight-loss
BOOKS REFERENCED
The Dorito Effect: The Surprising New Truth About Food and Flavor, by Mark Schatzker
amazon.com/The-Dorito-Effect-Mark-Schatzker-audiobook/dp/B00WXS745G/ref=sr_1_1
Salt Sugar Fat: How the Food Giants Hooked Us, by Michael Moss
amazon.com/Salt-Sugar-Fat-Michael-Moss-audiobook/dp/B00B4G0MMK/ref=sr_1_1
The Hungry Brain: Outsmarting the Instincts That Make Us Overeat, by Stephan Guyenet
amazon.com/The-Hungry-Brain-audiobook/dp/B01MY2QWYM/ref=sr_1_1
Nature Wants Us to Be Fat: The Surprising Science Behind Why We Gain Weight and How We Can Prevent--and Reverse--It, by Richard Johnson
amazon.com/Nature-Wants-Fat-Prevent-Reverse/dp/1637740344
Metabolical: The Lure and the Lies of Processed Food, Nutrition, and Modern Medicine, by Robert Lustig
amazon.com/Metabolical-Processed-Nutrition-Modern-Medicine/dp/B08LP21JLQ/ref=sr_1_1
The Nature of Nutrition: A Unifying Framework from Animal Adaptation to Human Obesity by Stephen J. Simpson, David Raubenheimer
amazon.com/Nature-Nutrition-Unifying-Framework-Adaptation-ebook/dp/B007BOKOFO/ref=sr_1_1
