Uploaded June 2025 | Updated September 2026, 2 weeks ago
Welcome to spotLights, the interview series that shines a spotlight on cutting-edge biological research and the brilliant minds behind it. spotLights is brought to you by preLights, the preprint highlights service run by the biological community and supported by The Company of Biologists.
In episode 14, recorded at the Biologists @ 100 conference in Liverpool, UK, we talk to Matteo Allegretti, a young group leader at the MRC Laboratory of Molecular Biology, Cambridge, UK. Matteo and his lab members aim to understand the molecular basis of how the nucleus is remodelled in shape during differentiation processes or due to environmental cues. Here, we discuss the preprints his lab recently posted (presented at the conference) on this topic.
Links to:
Preprint 1 - biorxiv.org/content/10.1101/2024.10.30.620797v2
Preprint 2 - biorxiv.org/content/10.1101/2025.01.17.633376v1
spotLight hosted by:
Jonathan Townson, Postdoc at University of Oslo, Norway
spotLight recorded and edited by:
Reinier Prosee, preLights Community Manager, The Company of Biologists
Welcome to spotLights, the interview series that shines a spotlight on cutting-edge biological research and the brilliant minds behind it. spotLights is brought to you by preLights, the preprint highlights service run by the biological community and supported by The Company of Biologists.
In episode 14, recorded at the Biologists @ 100 conference in Liverpool, UK, we talk to Matteo Allegretti, a young group leader at the MRC Laboratory of Molecular Biology, Cambridge, UK. Matteo and his lab members aim to understand the molecular basis of how the nucleus is remodelled in shape during differentiation processes or due to environmental cues. Here, we discuss the preprints his lab recently posted (presented at the conference) on this topic.
Links to:
Preprint 1 - biorxiv.org/content/10.1101/2024.10.30.620797v2
Preprint 2 - biorxiv.org/content/10.1101/2025.01.17.633376v1
spotLight hosted by:
Jonathan Townson, Postdoc at University of Oslo, Norway
spotLight recorded and edited by:
Reinier Prosee, preLights Community Manager, The Company of Biologists




![spotLights Ep 10: preLights in conversation with Helena Crellin
Welcome to spotLights, the interview series that shines a spotlight on cutting-edge biological research and the brilliant minds behind it. spotLights is brought to you by preLights, the preprint highlights service run by the biological community and supported by The Company of Biologists.
In this tenth episode, recorded at the Biologists @ 100 conference in Liverpool, UK, we talk to Helena Crellin, PhD student in the lab of Clare Buckley at the University of Cambridge, UK, and discuss the preprint she presented at the conference introducing a novel optogenetic technique in zebrafish.
Helena: “We were really excited by… [this] technical advance because it let us look at how forces are propagated through complex tissues during development.”
Link to preprint: https://doi.org/10.1101/2024.09.19.613826
spotLight hosted by: Jonathan Townson, Postdoc at University of Oslo, Norway
spotLight recorded and edited by: Reinier Prosee, preLights Community Manager, The Company of Biologists spotLights Ep 10: preLights in conversation with Helena Crellin](https://i.ytimg.com/vi/6uce4whDt2M/mqdefault.jpg)





