The Kings Monologue | SHOCKING stats about MELANIN, the SUN and SKIN CANCER they tried to hide!!! @kingmono | Uploaded August 2024 | Updated October 2024, 42 minutes ago.
The lowest incidence rates occurred in most regions of Africa and Asia, with rates less than 1 per 100 000 person-years (except for Middle and Southern Africa as well as Western Asia).
This information was taken from the Aim at Melanoma Foundation.
What is Cutaneous Melanoma?
Cutaneous or skin melanoma (also called malignant melanoma, although any diagnosis of melanoma is cancer even if “malignant” is not used) develops in pigment cells called melanocytes. These melanocytes produce melanin, the vital pigment that gives our skin its color and protects it from damage caused by ultraviolet (UV) rays from the sun or tanning devices. Cutaneous melanoma occurs when cancerous cells grow out of control (mutate) and crowd out normal cells. Usually, cutaneous melanoma begins in the epidermis—the top layer of skin—and can become invasive from there.
There are four main subtypes of cutaneous melanoma: superficial spreading melanoma; nodular melanoma; lentigo maligna melanoma; and acral lentiginous melanoma (ALM). Other subtypes, such as desmoplastic and amelanotic melanoma, also exist but are rare.
What is Acral Lentiginous Melanoma?
Acral lentiginous melanoma (ALM) is a specific type of melanoma that appears on the palms of the hands, the soles of the feet, or under the nails. The word “acral” means “extremity” in Greek and refers to the occurrence of this type of melanoma on the extremities (hands and feet). The word “lentiginous” refers to the fact that the spot of melanoma is often much darker than the surrounding skin.
Though relatively uncommon in the general population, ALM is the most common type of melanoma in people with darker skin and those of Asian descent. However, it can appear on all skin types.
Because of the misconceptions that melanomas only occur in sun-exposed areas and that people of color are not at risk for melanoma, these melanomas can be discovered later than other types, after they have invaded deeper layers of skin or metastasized.
This information was reported in the National Library pf Medicine in a report titled Acral lentiginous melanoma written by Kelly Hall
Continuing Education Activity
Acral lentiginous melanoma is a subtype of cutaneous malignant melanoma. It is comprised of malignant melanocytes, which can become invasive with time. It is often diagnosed at a later stage than the other forms of cutaneous malignant melanoma and in populations that are at a low risk for UV-induced melanomas, which highlights the need for early screening and detection.
It is the least common subtype of melanoma, comprising only 2 to 3% of total melanoma diagnoses. Unlike other CMM, UV-radiation is not thought to play a significant part in the development of ALM. It is most commonly on the lower extremities and is often advanced at the time of presentation leading to a high level of morbidity and mortality.
Incidence rates of ALM were highest in Hispanic Whites at 2.5 per 1,000,000 person-years and significantly lower in Blacks, Non-Hispanic Whites, and Asian/Pacific Islanders at 1.8, 1.8, and 1.1 per 1,000,000 person-years, respectively. Melanoma specific survival (MSS) was lower in Black and Hispanic White populations at 5 and 10 years than whites; however, when controlled for Breslow depth, no difference was seen. This is thought to be attributable to the advanced stage at presentation in these minority groups.
The following information was published by the Melanoma research alliance.
Acral melanoma, sometimes called acral lentiginous melanoma, is a rare subtype of melanoma that forms on the palms, soles of feet, or under finger or toe nails. Unlike cutaneous (skin) melanoma, it is not believed to be caused by sun exposure and therefore occurs in areas not typically exposed to the sun. Acral melanoma affects people of all races and ethnicities.
youtu.be/UKsTO43FgTM?si=WE3wFaf8VyzhvY6W - A shorter version of this video on my second channel - The King Mono Show
youtu.be/JQkjF-_tUuk?si=uxgDZiYqqPJNKegA - The video by Figure 1 - subscribe and support their channel!
Video by ROCKETMANN TEAM: pexels.com/video/close-up-video-of-hands-9465408
Video by ROCKETMANN TEAM: pexels.com/video/a-woman-s-legs-are-shown-in-a-close-up-9465188
jamanetwork.com/journals/jamadermatology/fullarticle/2790344#:~:text=This%20is%20in%20contrast%20to,females%20(151%20000%20cases)
youtube.com/shorts/zydQ9brD6KU?si=xPppmf3CTepttAn0
aimatmelanoma.org/melanoma-101/types-of-melanoma/cutaneous-melanoma/acral-lentiginous-melanoma
ncbi.nlm.nih.gov/books/NBK559113/#:~:text=Acral%20lentiginous%20melanoma%20(ALM)%2C,of%20the%20limbs%20(extremities)
curemelanoma.org/about-melanoma/types/acral-melanoma
The lowest incidence rates occurred in most regions of Africa and Asia, with rates less than 1 per 100 000 person-years (except for Middle and Southern Africa as well as Western Asia).
This information was taken from the Aim at Melanoma Foundation.
What is Cutaneous Melanoma?
Cutaneous or skin melanoma (also called malignant melanoma, although any diagnosis of melanoma is cancer even if “malignant” is not used) develops in pigment cells called melanocytes. These melanocytes produce melanin, the vital pigment that gives our skin its color and protects it from damage caused by ultraviolet (UV) rays from the sun or tanning devices. Cutaneous melanoma occurs when cancerous cells grow out of control (mutate) and crowd out normal cells. Usually, cutaneous melanoma begins in the epidermis—the top layer of skin—and can become invasive from there.
There are four main subtypes of cutaneous melanoma: superficial spreading melanoma; nodular melanoma; lentigo maligna melanoma; and acral lentiginous melanoma (ALM). Other subtypes, such as desmoplastic and amelanotic melanoma, also exist but are rare.
What is Acral Lentiginous Melanoma?
Acral lentiginous melanoma (ALM) is a specific type of melanoma that appears on the palms of the hands, the soles of the feet, or under the nails. The word “acral” means “extremity” in Greek and refers to the occurrence of this type of melanoma on the extremities (hands and feet). The word “lentiginous” refers to the fact that the spot of melanoma is often much darker than the surrounding skin.
Though relatively uncommon in the general population, ALM is the most common type of melanoma in people with darker skin and those of Asian descent. However, it can appear on all skin types.
Because of the misconceptions that melanomas only occur in sun-exposed areas and that people of color are not at risk for melanoma, these melanomas can be discovered later than other types, after they have invaded deeper layers of skin or metastasized.
This information was reported in the National Library pf Medicine in a report titled Acral lentiginous melanoma written by Kelly Hall
Continuing Education Activity
Acral lentiginous melanoma is a subtype of cutaneous malignant melanoma. It is comprised of malignant melanocytes, which can become invasive with time. It is often diagnosed at a later stage than the other forms of cutaneous malignant melanoma and in populations that are at a low risk for UV-induced melanomas, which highlights the need for early screening and detection.
It is the least common subtype of melanoma, comprising only 2 to 3% of total melanoma diagnoses. Unlike other CMM, UV-radiation is not thought to play a significant part in the development of ALM. It is most commonly on the lower extremities and is often advanced at the time of presentation leading to a high level of morbidity and mortality.
Incidence rates of ALM were highest in Hispanic Whites at 2.5 per 1,000,000 person-years and significantly lower in Blacks, Non-Hispanic Whites, and Asian/Pacific Islanders at 1.8, 1.8, and 1.1 per 1,000,000 person-years, respectively. Melanoma specific survival (MSS) was lower in Black and Hispanic White populations at 5 and 10 years than whites; however, when controlled for Breslow depth, no difference was seen. This is thought to be attributable to the advanced stage at presentation in these minority groups.
The following information was published by the Melanoma research alliance.
Acral melanoma, sometimes called acral lentiginous melanoma, is a rare subtype of melanoma that forms on the palms, soles of feet, or under finger or toe nails. Unlike cutaneous (skin) melanoma, it is not believed to be caused by sun exposure and therefore occurs in areas not typically exposed to the sun. Acral melanoma affects people of all races and ethnicities.
youtu.be/UKsTO43FgTM?si=WE3wFaf8VyzhvY6W - A shorter version of this video on my second channel - The King Mono Show
youtu.be/JQkjF-_tUuk?si=uxgDZiYqqPJNKegA - The video by Figure 1 - subscribe and support their channel!
Video by ROCKETMANN TEAM: pexels.com/video/close-up-video-of-hands-9465408
Video by ROCKETMANN TEAM: pexels.com/video/a-woman-s-legs-are-shown-in-a-close-up-9465188
jamanetwork.com/journals/jamadermatology/fullarticle/2790344#:~:text=This%20is%20in%20contrast%20to,females%20(151%20000%20cases)
youtube.com/shorts/zydQ9brD6KU?si=xPppmf3CTepttAn0
aimatmelanoma.org/melanoma-101/types-of-melanoma/cutaneous-melanoma/acral-lentiginous-melanoma
ncbi.nlm.nih.gov/books/NBK559113/#:~:text=Acral%20lentiginous%20melanoma%20(ALM)%2C,of%20the%20limbs%20(extremities)
curemelanoma.org/about-melanoma/types/acral-melanoma
