Uploaded May 2024 | Updated September 2026, 2 weeks ago
The Oni lab seeks to uncover the elements of effective anti-tumor immunity and develop novel antibody-based tools to induce tumor clearance by immune effector cells. The lab focuses on pancreatic cancer, a highly lethal malignancy with limited treatment options, with the ultimate goal of inspiring the development of breakthrough therapies for this deadly disease. Oni’s graduate work focused on developing tools for the early detection of pancreatic cancer, and on identifying the mechanisms that drive malignant progression—which can become targets for new therapeutics. He also helped develop one of the first mouse and human organoid models of pancreatic cancer, which he used to identify tumor-specific metabolic vulnerabilities and resistance pathways. His current work focuses on uncovering mechanisms for the poor anti-tumor immune response to pancreatic cancer, and developing novel ways of promoting tumor clearance by immune cells. He hopes to uncover new avenues and develop tools for targeting pancreatic cancer in order to improve patient outcomes, inspire and mentor the next generation of scientists from diverse backgrounds, and build collaborative networks across disciplines to solve some of the most challenging biological questions.
scholar.google.com/citations?user=Ky4TtmsAAAAJ&hl=en
#biotechnology #science #vc #startup #startups #startupideas #biology #biotech #chemistry #business #speech #speeches #investing #investment #lifescience #casestudy #scientist #scientists #inventors #inventor #inventions #invention #research #innovation #siliconvalley #entrepreneur #entrepreneurship #entrepreneurs #healthcare #genomics #genetics #history #biologia #technology #tech #founderstories #founder #founders #founderstory #scienceandtechnology #sciencestory #stories #bioengineering #engineering #engineer #biochemistry #discovery #discover #technical #health #education #educational #learning #learn #podcast #podcasts #podcasting #podcaster #technews
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The Oni lab seeks to uncover the elements of effective anti-tumor immunity and develop novel antibody-based tools to induce tumor clearance by immune effector cells. The lab focuses on pancreatic cancer, a highly lethal malignancy with limited treatment options, with the ultimate goal of inspiring the development of breakthrough therapies for this deadly disease. Oni’s graduate work focused on developing tools for the early detection of pancreatic cancer, and on identifying the mechanisms that drive malignant progression—which can become targets for new therapeutics. He also helped develop one of the first mouse and human organoid models of pancreatic cancer, which he used to identify tumor-specific metabolic vulnerabilities and resistance pathways. His current work focuses on uncovering mechanisms for the poor anti-tumor immune response to pancreatic cancer, and developing novel ways of promoting tumor clearance by immune cells. He hopes to uncover new avenues and develop tools for targeting pancreatic cancer in order to improve patient outcomes, inspire and mentor the next generation of scientists from diverse backgrounds, and build collaborative networks across disciplines to solve some of the most challenging biological questions.
scholar.google.com/citations?user=Ky4TtmsAAAAJ&hl=en
#biotechnology #science #vc #startup #startups #startupideas #biology #biotech #chemistry #business #speech #speeches #investing #investment #lifescience #casestudy #scientist #scientists #inventors #inventor #inventions #invention #research #innovation #siliconvalley #entrepreneur #entrepreneurship #entrepreneurs #healthcare #genomics #genetics #history #biologia #technology #tech #founderstories #founder #founders #founderstory #scienceandtechnology #sciencestory #stories #bioengineering #engineering #engineer #biochemistry #discovery #discover #technical #health #education #educational #learning #learn #podcast #podcasts #podcasting #podcaster #technews
Axial Newsletter: axial.substack.com
Build with Axial: build.axialvc.com
https://linktr.ee/axialxyz
