Uploaded December 2025 | Updated September 2026, 1 week ago

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San Francisco 49ers vs Indianapolis Colts NFL Week 16 Live Game Stream
49ers vs Colts Live Stream NFL Week 16 December 22 2025
San Francisco 49ers vs Indianapolis Colts Live Commentary and Reaction
Live Play by Play for 49ers vs Colts Week 16 NFL Live Stream

Mitch of TheBottomLineView is LIVE for NFL Week 16 on Monday Night December 22 2025! Indianapolis Colts host San Francisco 49ers on monday night football! Kyle Shanahan and Brock Purdy are on the road to take on Phillip Rivers and Jonathan Taylor’s Colts! Join Mitch live for play by play, analysis and live reaction to the 49ers vs Colts! Who will win?

#nfl #49ers #colts