Rouleaux Formation EXPLAINED | Why RBCs Stack Like Coins! πŸ”¬πŸ©Έ @AladdinCreations
Rouleaux Formation EXPLAINED | Why RBCs Stack Like Coins! πŸ”¬πŸ©Έ  @AladdinCreations
Uploaded December 2025 | Updated September 2026, 1 hour ago
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My Name Is Kavindu Lakmal , Medical Laboratory Scientist graduated From University Of Peradeniya.


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What is Rouleaux Formation?

Rouleaux formation occurs when red blood cells stack together like a roll of coins due to increased plasma proteins such as fibrinogen and immunoglobulins.
This reduces the normal repulsive forces between RBCs and leads to characteristic stacking on a peripheral blood smear.

In this detailed hematology lesson, you will learn:
πŸ”¬ How rouleaux formation appears on a blood smear
πŸ§ͺ Why increased plasma proteins cause RBC stacking
πŸ“Œ Common clinical conditions associated with rouleaux formation:
β€’ Multiple Myeloma
β€’ WaldenstrΓΆm Macroglobulinemia
β€’ Chronic infections
β€’ Autoimmune and inflammatory disorders
🧠 How to differentiate rouleaux formation vs RBC agglutination
πŸŽ“ High-yield points for MLS / MLT exams and routine smear reporting

This video is ideal for:
βœ” Medical Laboratory Science Students
βœ” Medical Students
βœ” Lab Technologists & Technicians
βœ” Anyone learning RBC morphology and blood smear interpretation

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#RouleauxFormation #RBCMorphology #Hematology #MedicalLaboratoryScience #MLS #MLT #BloodSmear #Microscopy #MultipleMyeloma #AladdinCreations

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