Uploaded April 2022 | Updated September 2026, 1 week ago
Stop memorizing and start recognizing. Organic chemistry mechanisms are built on just four fundamental patterns. Once you master these, you can predict almost any reaction, from SN1/SN2/E1/E2 to complex carbonyl chemistry.
📘Master the Mechanisms! Grab the Organic Chemistry Reaction Mechanisms Survival Guide: payhip.com/b/rYbBp
🧠Full Mechanisms Playlist: youtube.com/playlist?list=PLvUW25kBaMMtvqt_IBtezyBX_kk447pxZ
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🧬If you need a refresher on chirality for mechanisms to make sense, start here: youtube.com/playlist?list=PLvUW25kBaMMupOdw1Wgy8YauiQ40J_5nx
⚗️For all of my ochem videos in one place: youtube.com/playlist?list=PLvUW25kBaMMuKRkW9gDV7vlAk4Y9WRU7c
🥼If you need to take the MCAT: youtube.com/playlist?list=PLvUW25kBaMMuJZI5IVWO8X0syBANn-YqY
In this video, we break down the "grammar of curve arrows" so you can understand why electrons move, not just where they go.
The 4 Patterns:
• Proton Transfer
• Dissociation (Loss of a Leaving Group)
• Nucleophilic Attack (The most common bond-forming step)
• Rearrangement: Recognizing when hydride or methyl shift occurs
🧪 For the chemist who prefers eyebrows: Grab the complete collection of 11 hand-drawn lab safety posters: payhip.com/b/SNQL0
🔬As an Amazon Affiliate, I earn from qualifying purchases at no extra cost to you. Start your shopping here: amazon.com/shop/chemnut?ccs_id=11f20bce-5f74-427b-85fb-bdf66849405a
Time Stamps:
0:00 The Logic of Patterns
0:39 Pattern 1: Proton Transfer
4:15 Pattern 2: Dissociation
6:41 Pattern 3: Nucleophilic Attack/Addition
10:24 Pattern 4: Rearrangement
13:34 How to Use These Patterns
#OrganicChemistry #ChemistryEducation #ReactionMechanism #ChemistryTrick
Stop memorizing and start recognizing. Organic chemistry mechanisms are built on just four fundamental patterns. Once you master these, you can predict almost any reaction, from SN1/SN2/E1/E2 to complex carbonyl chemistry.
📘Master the Mechanisms! Grab the Organic Chemistry Reaction Mechanisms Survival Guide: payhip.com/b/rYbBp
🧠Full Mechanisms Playlist: youtube.com/playlist?list=PLvUW25kBaMMtvqt_IBtezyBX_kk447pxZ
🍵Buy the Professor a tea to keep the videos coming: patreon.com/c/ChemistryinaNutshell
🧬If you need a refresher on chirality for mechanisms to make sense, start here: youtube.com/playlist?list=PLvUW25kBaMMupOdw1Wgy8YauiQ40J_5nx
⚗️For all of my ochem videos in one place: youtube.com/playlist?list=PLvUW25kBaMMuKRkW9gDV7vlAk4Y9WRU7c
🥼If you need to take the MCAT: youtube.com/playlist?list=PLvUW25kBaMMuJZI5IVWO8X0syBANn-YqY
In this video, we break down the "grammar of curve arrows" so you can understand why electrons move, not just where they go.
The 4 Patterns:
• Proton Transfer
• Dissociation (Loss of a Leaving Group)
• Nucleophilic Attack (The most common bond-forming step)
• Rearrangement: Recognizing when hydride or methyl shift occurs
🧪 For the chemist who prefers eyebrows: Grab the complete collection of 11 hand-drawn lab safety posters: payhip.com/b/SNQL0
🔬As an Amazon Affiliate, I earn from qualifying purchases at no extra cost to you. Start your shopping here: amazon.com/shop/chemnut?ccs_id=11f20bce-5f74-427b-85fb-bdf66849405a
Time Stamps:
0:00 The Logic of Patterns
0:39 Pattern 1: Proton Transfer
4:15 Pattern 2: Dissociation
6:41 Pattern 3: Nucleophilic Attack/Addition
10:24 Pattern 4: Rearrangement
13:34 How to Use These Patterns
#OrganicChemistry #ChemistryEducation #ReactionMechanism #ChemistryTrick



![The Benzene Puzzle [Part 1]
Can you figure out the structure of benzene from the data we had in the 1800s? It certainly eluded early chemists for a long time!
Watch the whole playlist. Can you solve the puzzle before Kekule? https://www.youtube.com/playlist?list=PLvUW25kBaMMvs5nsG1VUQA0wsP9LGEQha
Playlists to ACE Chemistry:
https://www.youtube.com/playlist?list=PLvUW25kBaMMuKRkW9gDV7vlAk4Y9WRU7c
https://www.youtube.com/playlist?list=PLvUW25kBaMMssGHFrR4Ee7 8cFBvBkgN
https://www.youtube.com/playlist?list=PLvUW25kBaMMs9m0GL4dz8jSs0K4PWfqCp
https://www.youtube.com/playlist?list=PLvUW25kBaMMuHwUffHLOozSFQ0Cz_iTnC
https://www.youtube.com/playlist?list=PLvUW25kBaMMv7_3jTEAe3vVZqPhsjf5Oy
https://www.youtube.com/playlist?list=PLvUW25kBaMMtc45U4K2b0Dm88L9D7d0EE
🍵Buy the Professor a tea to keep the videos coming: https://www.patreon.com/c/ChemistryinaNutshell
🧪 For the chemist who prefers eyebrows: Grab the complete collection of 11 hand-drawn lab safety posters: https://payhip.com/b/SNQL0
🔬As an Amazon Affiliate, I earn from qualifying purchases at no extra cost to you. Start your shopping here: https://www.amazon.com/shop/chemnut?ccs_id=11f20bce-5f74-427b-85fb-bdf66849405a
Time Stamps:
0:00 Introduction
Pre-1865
0:31 Molecular Formula of C6H6 and 4 Degrees of Unsaturation
5:25 Unusual Stability
5:34 No Electrophilic Addition Reactions / No C=C
6:56 Substitution Products / Equivalent Hydrogens
8:02 Ethane & Propane Substitutions & Equivalent Hydrogens
The 1865 Challenge
9:54 Propose a Structure of Benzene Give Information Available in 1865
10:29 Answers from 1865
1865 - 1890
13:15 Kekulés 1865 proposition that 2 different 1,2-disubstituted products are indistinguishable
*** Mistake: Kekulé never used his first given name (Friedrich); he was known throughout his life as August Kekulé.
13:31 Dewar and Ladenburg Structures
Citations:
Organic Chemistry, 8th ed. Bruice, Paula Yurkanis. 2016. Pearson. Chapter 8
#benzene #puzzle #chemistry The Benzene Puzzle [Part 1]](https://i.ytimg.com/vi/W2BysSrl7Hs/mqdefault.jpg)






