Uploaded November 2013 | Updated September 2026, 1 day ago
This presentation by Angeli Maun Akey, M.D was given at the 14th Clinical Applications for Age Management Medicine Conference.
Dr. Akey reviews the current understanding of progesterone and the brain. From a review of studies performed in animal models on the importance of progesterone and other neuroactive steroids in brain stabilization, to NIH phase 2 and 3 clinical trials of IV progesterone use in acute traumatic brain injury (the "PROTECT" and "SYNAPSE" trials respectively), there is mounting evidence of the importance of progesterone in both men and women. This presentation leads credence to the use of bioidentical progesterone in the luteal phase for treatment of premenstrual syndrome (PMS) and in hysterectomized women for the observed effect of mood stabilization and sleep quality.
What is Age Management Medicine?
Age Management Medicine is a proactive, preventive approach focused on preservation of optimum human function and quality of life, making every effort to modulate the process of aging prior to the onset of degenerative aging. The basic tenets of Age Management Medicine are patient evaluation through extensive medical history, lifestyle assessment, physical examination and laboratory evaluation to establish personalized proactive treatment plans consisting of proper diet, exercise, stress management and appropriate medical interventions.
About AMMG
It is the goal of the Age Management Medicine Group (AMMG) to provide education and information on the specialty of Age Management Medicine to physicians and healthcare professionals through evidence-based, continuing medical education conferences, workshops, seminars, publications and Web media. The Group consists of leading industry healthcare professionals, physicians, practitioners, researchers, medical
associations and providers of products and services.
For more information about this presentation or the AMMG Conference visit our website at agemed.org
This presentation by Angeli Maun Akey, M.D was given at the 14th Clinical Applications for Age Management Medicine Conference.
Dr. Akey reviews the current understanding of progesterone and the brain. From a review of studies performed in animal models on the importance of progesterone and other neuroactive steroids in brain stabilization, to NIH phase 2 and 3 clinical trials of IV progesterone use in acute traumatic brain injury (the "PROTECT" and "SYNAPSE" trials respectively), there is mounting evidence of the importance of progesterone in both men and women. This presentation leads credence to the use of bioidentical progesterone in the luteal phase for treatment of premenstrual syndrome (PMS) and in hysterectomized women for the observed effect of mood stabilization and sleep quality.
What is Age Management Medicine?
Age Management Medicine is a proactive, preventive approach focused on preservation of optimum human function and quality of life, making every effort to modulate the process of aging prior to the onset of degenerative aging. The basic tenets of Age Management Medicine are patient evaluation through extensive medical history, lifestyle assessment, physical examination and laboratory evaluation to establish personalized proactive treatment plans consisting of proper diet, exercise, stress management and appropriate medical interventions.
About AMMG
It is the goal of the Age Management Medicine Group (AMMG) to provide education and information on the specialty of Age Management Medicine to physicians and healthcare professionals through evidence-based, continuing medical education conferences, workshops, seminars, publications and Web media. The Group consists of leading industry healthcare professionals, physicians, practitioners, researchers, medical
associations and providers of products and services.
For more information about this presentation or the AMMG Conference visit our website at agemed.org
