The Company of Biologists | Pre- and postsynaptic structures in a 14-month-old brain organoid @CompanyofBiologists | Uploaded November 2022 | Updated October 2024, 10 hours ago.
In our Special Issue: Modelling Development In Vitro, Juan Eduardo Rodriguez-Gatica, Vira Iefremova, Oliver Brüstle, Martin Karl Schwarz, Ulrich Kubitscheck and colleagues introduce their system to combine tissue expansion and light-sheet fluorescence microscopy for imaging organoid development. The highlighted movie shows pre- and postsynaptic structures in a 14-month-old brain organoid, labelled with synapsin 1 and Homer1.

journals.biologists.com/dev/article/149/20/dev200439/276224/Imaging-three-dimensional-brain-organoid