Uploaded September 2026 | Updated September 2026, 3 weeks ago

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Path of Exile 2, but I turned it into a Pokémon Nuzlocke challenge run

One life. One equippable item per zone. No zone resets. No Life Flasks during boss fights. One vendor purchase per Act.

What followed was a PoE 2 Challenge Run full of of terrible loot, cursed crafting, almost no Support Gems, and enough clenching to qualify as a medical condition.

Can a Vegan Oracle survive the PoE 2 Ultra Hardcore Nuzlocke Challenge?

If you enjoy Path of Exile 2 challenge runs, Hardcore gameplay, and watching bad decisions become content, subscribe and let me know what I should regret next.

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Links:
► Twitch: twitch.tv/lolcohol
► Discord: discord.gg/lolcoholics-anonymous-808351622547505162
► Patreon: patreon.com/lolcohol
Become a Member: youtube.com/@Lolcohol/membership

► My Mobalytics Page: tinyurl.com/vk6ppaa7
► PoE 2 Mobalytics: mobalytics.gg/poe-2

► PoE Profile:
pathofexile.com/account/view-profile/Lolcohol-4777
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Chapters:
0:00 The Ultra Hardcore Nuzlocke Challenge
1:27 Rules 1 & 2 – The Riverbank
2:44 Act 1 – Clearfell
7:19 Rule 4 – One Vendor Purchase
11:29 King in the Mists & Ogham
15:32 Ogham Manor & Count Geonor
17:53 Act 2 – The Vastiri Desert
21:38 Rudja & Jamanra
25:13 The Bone Pits & Titan Grotto
30:36 Tor Gul, The Dreadnought & Jamanra
35:03 Act 3 – The Jungles of Utzaal
40:50 Jiquani, Zicoatl & Ascendancy
44:29 No Flasks, Queen of Filth & Viper
50:49 Doryani
52:20 Act 4 – The Islands
54:55 Captain Hartlin, Krutog & Scourge
58:04 Diamora & The Halls of the Dead
1:01:18 Yama the White
1:03:44 The Run Ends
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#PathOfExile2 #PoE2 #Nuzlocke #Hardcore #challengerun

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