Uploaded August 2024 | Updated September 2026, 2 weeks ago
Dr. Zacharie Taoufiq, a neuroscientist at OIST, discusses his groundbreaking work on personalized synapse proteomics. This innovative technology aims to address the challenges in diagnosing and treating neuropsychiatric disorders. By recreating neurons from patients' blood samples and analyzing synaptic protein composition, Dr. Taoufiq's team can access crucial brain molecular information from living patients. Their research has successfully differentiated between schizophrenia and healthy individuals using AI algorithms. The ultimate goal is to support the development of personalized therapies for psychiatric disorders, potentially transforming diagnosis and treatment approaches in neuroscience and psychiatry.
#BrainDiseases #StemCells #Proteomics #PsychiatricDisorders
Dr. Zacharie Taoufiq, a neuroscientist at OIST, discusses his groundbreaking work on personalized synapse proteomics. This innovative technology aims to address the challenges in diagnosing and treating neuropsychiatric disorders. By recreating neurons from patients' blood samples and analyzing synaptic protein composition, Dr. Taoufiq's team can access crucial brain molecular information from living patients. Their research has successfully differentiated between schizophrenia and healthy individuals using AI algorithms. The ultimate goal is to support the development of personalized therapies for psychiatric disorders, potentially transforming diagnosis and treatment approaches in neuroscience and psychiatry.
#BrainDiseases #StemCells #Proteomics #PsychiatricDisorders
![Feng Liu: Excitonic Bose Einstein Condensation in Flat Bands (TSVP Talk at OIST)
Find out more about the TSVP on the program website: https://www.oist.jp/visiting-program.
Abstract: An excitonic insulator (EI) phase can be stabilized in narrow-gap semiconductors/semimetals when spontaneously formed excitons, bound bosonic pairs of electrons and holes, condense at low temperatures. The search for excitonic Bose-Einstein condensate (BEC) in intrinsic semiconductors has received tremendous attention in the past decade, but so far convincing evidence remains lacking. Several material candidates have been recently proposed computationally, but these studies are limited to single exciton calculations and the effects of interactions, if included, are approximated using mean-field approach. In this talk, I will discuss our recent work investigating the role of topological flat bands (FBs) in promoting excitonic BEC. First, I will show that flat valence and conduction bands (so-called yin-yang FBs) of quantum semiconductors [1], such as the one having a diatomic Kagome lattice as exemplified in a superatomic graphene, conspire to indicate a triplet EI state, based on DFT-GW and BSE calculations for a single exciton formation. Next, using exact diagonalization method to solve an extended Hubbard lattice model of yin-yang FBs, I will show directly spontaneous BEC of triplet excitons, based on analyses of multi-exciton formation energies and wave functions [2]. I will demonstrate the critical role of FBs in promoting quantum coherence, as evidenced by off-diagonal long-range order in many-exciton states. These works significantly enriches FB and excitonic physics while providing a unique platform for material realization of spinor BEC and spin superfluidity.
Profile: Feng Liu received his B.Sc. in Engineering physics from Tsinghua University in 1984 and earned his Ph.D. in 1990 at Virginia Commonwealth University in Chemical physics. He is currently a Distinguished and Ivan B. Cutler endowed chair Professor in the Department of Materials Science and Engineering at the University of Utah. His research interests lie in the theoretical modeling and computer simulation, from electronic to atomic and to mesoscopic scales, to study a wide spectrum of physical behavior of materials, with a special focus on surfaces/interfaces, thin films and low-dimensional materials. His best-known work includes theoretical modeling of strain-induced self-assembly of quantum dots and quantum wires in epitaxial growth of thin films, prediction of organic two-dimensional topological materials and surface-based topological states, and prediction of many-body quantum states of yin-yang flat bands. He is recipient of 2023 American Physical Society Davisson-Germer Prize in Surface Physics. He is a Fellow of American Physical Society. He served as Divisional Associated Editor of Physical Review Letters. He is a founding editor-in-chief for Coshare Science, a new international journal of video research articles.
#OIST #OIST_TSVP #Theoretical #Science #VisitingProgram #Okinawa #TSVP Feng Liu: Excitonic Bose Einstein Condensation in Flat Bands (TSVP Talk at OIST)](https://i.ytimg.com/vi/XOZ9nIou5JE/mqdefault.jpg)









