Uploaded August 2025 | Updated September 2026, 2 weeks ago

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Brain in a Jar is a brand new item introduced in the Epiphany mod for The Binding of Isaac as of the Wave 7.5 update that released on August 9th, 2025. It is one of 18 unlockable milestone items that are acquired by unlocking a set percentage of all of Epiphany's achievements.

Check out Liquid Nitrogen at IsaacGuru.com: isaacguru.com/mod/epiphany/item/Brain_in_a_Jar
Download Epiphany: steamcommunity.com/sharedfiles/filedetails/?id=3012430463
Soundtrack used in the video - Old Testament by Excelsior: youtu.be/7XO8K9nDTn0
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