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History with Kayleigh | Neanderthal Gene Variants Slow Drug Metabolism @HistoryWithKayleigh | Uploaded July 2022 | Updated October 2024, 8 hours ago.
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Way back in the day when Neanderthals and Homo sapiens lived together in the same area they interbred, but little did they know that this interbreeding between these 2 species could have quite the effect on the health of us modern humans.
The question arises, can ancient Neanderthal genes passed down some tens of thousands of years ago have an effect on the way drugs metabolize in individuals carrying these gene variants?

Enzymes CYP450, CYP2C9*1, CYP2C9*2, CYP2C8, CYP2C8*3


#NeanderthalGenes #Genevariants #NeanderthalEnzymes

Music: Adrian von Ziegler
Sources:
nature.com/articles/s41397-022-00284-6
ncbi.nlm.nih.gov/pmc/articles/PMC6202974
https://report.az/en/interesting/scientists-identify-neandertal-gene-variants-that-can-slow-drug-metabolism/
iflscience.com/your-neanderthal-genes-may-mean-you-metabolize-drugs-less-efficiently-64437
northcarolinatime.com/ancient-neanderthal-gene-variants-may-slow-drug-metabolism/62153
https://funancial.news/ancient-neanderthal-gene-variants-may-slow-drug-metabolism/
techphoenix.in/historical-neanderthal-gene-variants-can-gradual-drug-metabolism
newatlas.com/biology/ancient-neanderthal-gene-variants-slow-drug-metabolism
en.wikipedia.org/wiki/Cytochrome_P450



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