Uploaded January 2024 | Updated September 2026, 1 week ago
Muscle Abnormalities Worsen in Post Exertional Malaise
In this amazing study the Dutch researchers used muscle biopsies in the long COVID patients suffering from post-exertional malaise. They found that the muscle phenotype had changed resulting in lower excercise capacity. They also found mitochondrial function issues, and local amyloid accumulation. Macrophages and CD3+ T cells were also infiltrated in the muscle tissues. Let's review.
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Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
Muscle abnormalities worsen after post-exertional malaise in long COVID - Nature Communications
nature.com/articles/s41467-023-44432-3
A discovery in the muscles of long COVID patients may explain exercise troubles
npr.org/sections/health-shots/2024/01/09/1223077307/long-covid-exercise-post-exertional-malaise-mitochondria
A central role for amyloid fibrin microclots in long COVID/PASC: origins and therapeutic implications - PubMed
pubmed.ncbi.nlm.nih.gov/35195253
Amyloidosis: Definition of Amyloid and Amyloidosis, Classification Systems, Systemic Amyloidoses
emedicine.medscape.com/article/335414-overview
Treating the Most Disruptive Symptoms First and Preventing Worsening of Symptoms | Clinical Care of Patients | Healthcare Providers | Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) | CDC
cdc.gov/me-cfs/healthcare-providers/clinical-care-patients-mecfs/treating-most-disruptive-symptoms.html
Muscle Fatigue: Lactic Acid or Inorganic Phosphate the Major Cause? | Physiology
journals.physiology.org/doi/full/10.1152/physiologyonline.2002.17.1.17#:~:text=Intracellular%20acidosis%20due%20mainly%20to,cause%20of%20skeletal%20muscle%20fatigue.
Science Fact or Science Fiction? Lactic Acid Buildup Causes Muscle Fatigue and Soreness | Pfizer
pfizer.com/news/articles/science_fact_or_science_fiction_lactic_acid_buildup_causes_muscle_fatigue_and_soreness
Glycolysis - Wikipedia
en.wikipedia.org/wiki/Glycolysis
Human Skeletal Muscle Fiber Type Classifications
academic.oup.com/ptj/article/81/11/1810/2857618
Muscle Fiber Type Transitions with Exercise Training: Shifting Perspectives
ncbi.nlm.nih.gov/pmc/articles/PMC8473039
Muscle Hypertrophy - an overview | ScienceDirect Topics
sciencedirect.com/topics/medicine-and-dentistry/muscle-hypertrophy
Muscle abnormalities worsen after post-exertional malaise in long COVID - Nature Communications
nature.com/articles/s41467-023-44432-3
A discovery in the muscles of long COVID patients may explain exercise troubles
npr.org/sections/health-shots/2024/01/09/1223077307/long-covid-exercise-post-exertional-malaise-mitochondria
Muscle Abnormalities Worsen in Post Exertional Malaise
In this amazing study the Dutch researchers used muscle biopsies in the long COVID patients suffering from post-exertional malaise. They found that the muscle phenotype had changed resulting in lower excercise capacity. They also found mitochondrial function issues, and local amyloid accumulation. Macrophages and CD3+ T cells were also infiltrated in the muscle tissues. Let's review.
If you like this content and want more, click here: drbeen.com
Want to support this work?:
Become my patron: patreon.com/mobeensyed?fan_landing=true
PayPal: paypal.me/mobeensyed?locale.x=en_US
#drbeen #koolbeens #COVID
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
Muscle abnormalities worsen after post-exertional malaise in long COVID - Nature Communications
nature.com/articles/s41467-023-44432-3
A discovery in the muscles of long COVID patients may explain exercise troubles
npr.org/sections/health-shots/2024/01/09/1223077307/long-covid-exercise-post-exertional-malaise-mitochondria
A central role for amyloid fibrin microclots in long COVID/PASC: origins and therapeutic implications - PubMed
pubmed.ncbi.nlm.nih.gov/35195253
Amyloidosis: Definition of Amyloid and Amyloidosis, Classification Systems, Systemic Amyloidoses
emedicine.medscape.com/article/335414-overview
Treating the Most Disruptive Symptoms First and Preventing Worsening of Symptoms | Clinical Care of Patients | Healthcare Providers | Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) | CDC
cdc.gov/me-cfs/healthcare-providers/clinical-care-patients-mecfs/treating-most-disruptive-symptoms.html
Muscle Fatigue: Lactic Acid or Inorganic Phosphate the Major Cause? | Physiology
journals.physiology.org/doi/full/10.1152/physiologyonline.2002.17.1.17#:~:text=Intracellular%20acidosis%20due%20mainly%20to,cause%20of%20skeletal%20muscle%20fatigue.
Science Fact or Science Fiction? Lactic Acid Buildup Causes Muscle Fatigue and Soreness | Pfizer
pfizer.com/news/articles/science_fact_or_science_fiction_lactic_acid_buildup_causes_muscle_fatigue_and_soreness
Glycolysis - Wikipedia
en.wikipedia.org/wiki/Glycolysis
Human Skeletal Muscle Fiber Type Classifications
academic.oup.com/ptj/article/81/11/1810/2857618
Muscle Fiber Type Transitions with Exercise Training: Shifting Perspectives
ncbi.nlm.nih.gov/pmc/articles/PMC8473039
Muscle Hypertrophy - an overview | ScienceDirect Topics
sciencedirect.com/topics/medicine-and-dentistry/muscle-hypertrophy
Muscle abnormalities worsen after post-exertional malaise in long COVID - Nature Communications
nature.com/articles/s41467-023-44432-3
A discovery in the muscles of long COVID patients may explain exercise troubles
npr.org/sections/health-shots/2024/01/09/1223077307/long-covid-exercise-post-exertional-malaise-mitochondria
