Uploaded August 2011 | Updated September 2026, 1 week ago
This two-photon fluorescence image sequence shows the formation of a localized photothrombotic clot in a surface arteriole. The fluctuating, streaked appearance of the vessels is due to the motion of red blood cells and indicates flow. A saturated white strip at the top of the frame indicates irradiation with 523-nm light. Clot material is formed just downstream from the irradiated region. David Kleinfeld, University of California, San Diego.
This footage was taken as part of a project supported by NIBIB:
"Two-photon imaging of cortical surface microvessels reveals a robust redistribution in blood flow after vascular occlusion. C. B. Schaffer, B. Friedman, N. Nishimura, L. F. Schroeder, P. S. Tsai, F. F. Ebner, P. D. Lyden and D. Kleinfeld. Public Library of Science: Biology (2006) 4:258-270"
http://physics.ucsd.edu/neurophysics/publications/andy_shih_JCBFM_review.pdf
This two-photon fluorescence image sequence shows the formation of a localized photothrombotic clot in a surface arteriole. The fluctuating, streaked appearance of the vessels is due to the motion of red blood cells and indicates flow. A saturated white strip at the top of the frame indicates irradiation with 523-nm light. Clot material is formed just downstream from the irradiated region. David Kleinfeld, University of California, San Diego.
This footage was taken as part of a project supported by NIBIB:
"Two-photon imaging of cortical surface microvessels reveals a robust redistribution in blood flow after vascular occlusion. C. B. Schaffer, B. Friedman, N. Nishimura, L. F. Schroeder, P. S. Tsai, F. F. Ebner, P. D. Lyden and D. Kleinfeld. Public Library of Science: Biology (2006) 4:258-270"
http://physics.ucsd.edu/neurophysics/publications/andy_shih_JCBFM_review.pdf
