Uploaded September 2026 | Updated September 2026, 2 hours ago
Unlike many structural biology techniques that capture a single moment in time, nuclear magnetic resonance (NMR) spectroscopy allows scientists to study proteins as they move, fold and interact in solution.
At Scripps Research, scientists use NMR to investigate the molecular dynamics that shape biological function. By revealing how proteins change over time and respond to their environment, NMR provides insights into disease mechanisms, drug-target interactions and the development of new therapeutics.
During the Live Broadcast, Professor Jason Chen, executive director of Core Facilities, guided viewers through each stage of the NMR workflow.
Graduate student Madison Wagner demonstrated how samples are prepared for analysis in the laboratory of Professor Keary Engle, dean of Graduate & Postdoctoral Studies.
As the sample processed, NMR manager Gerard Kroon explained how the technology works and supports research across the institute.
Assistant Professor Megan Ken showed how her laboratory uses NMR to characterize RNA structural dynamics, identify rare, high-energy RNA conformations and advance small-molecule drug discovery.
https://www.scripps.edu/
Unlike many structural biology techniques that capture a single moment in time, nuclear magnetic resonance (NMR) spectroscopy allows scientists to study proteins as they move, fold and interact in solution.
At Scripps Research, scientists use NMR to investigate the molecular dynamics that shape biological function. By revealing how proteins change over time and respond to their environment, NMR provides insights into disease mechanisms, drug-target interactions and the development of new therapeutics.
During the Live Broadcast, Professor Jason Chen, executive director of Core Facilities, guided viewers through each stage of the NMR workflow.
Graduate student Madison Wagner demonstrated how samples are prepared for analysis in the laboratory of Professor Keary Engle, dean of Graduate & Postdoctoral Studies.
As the sample processed, NMR manager Gerard Kroon explained how the technology works and supports research across the institute.
Assistant Professor Megan Ken showed how her laboratory uses NMR to characterize RNA structural dynamics, identify rare, high-energy RNA conformations and advance small-molecule drug discovery.
https://www.scripps.edu/
