Uploaded February 2026 | Updated September 2026, 3 weeks ago

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The MiSeq™ i100 Series, Illumina’s latest benchtop sequencer, features a simplified workflow, fast turnaround time, and rapid sample-to-analysis capability enabled by the newly developed XLEAP-SBS chemistry. This Tech Support webinar will provide a comprehensive overview of the MiSeq i100 Series, covering the overall system workflow, analytical applications, and performance. It is designed to help both new users and experienced professionals understand the streamlined workflow and expanded sequencing capabilities offered by the MiSeq i100 Series.

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A global genomics leader, Illumina provides comprehensive next-generation sequencing solutions to the research, clinical, and applied markets. Through collaborative innovation, Illumina is fueling groundbreaking advancements in oncology, reproductive health, genetic disease, microbiology, agriculture, forensic science, and beyond.

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00:00 Introduction
00:43 MiSeq i100 Overview
04:57 Applications and Performance
12:03 Instrument Run Setup
14:12 First Time Setup
16:10 Options to Setup a Run
24:50 Maintenance & Troubleshooting Resources
35:43 DRAGEN Secondary Analysis
42:47 Reviewing Demultiplexing Results
44:34 Reviewing Run Performance
53:25 Resources