Uploaded August 2025 | Updated September 2026, 1 hour ago

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Our friends at OpenAI have released the GA version of their Realtime API! In this video we’ll show you how to use it with Twilio to build a speech-to-speech voice assistant. We’ll start from the video/repository we made for the beta, update it for GA, and make a few quality of life improvements in the code. You’ll be up and running with a voice bot powered by OpenAI Realtime API and Twilio in just minutes.

💻 Sign up for a Twilio account here: twil.io/trytwilio-yt
👉 Subscribe for more Twilio updates: twil.io/sub-twiliodevs

Learn more:
Twilio blog post: twil.io/openai-rt-py-ga
TwiML voices: twi.io/say-voices
Twilio Dev Phone: twil.io/dev-phone

Original Github repo: github.com/twilio-samples/speech-assistant-openai-realtime-api-python

Chapters:
00:00 Intro
00:11 Realtime API goes GA
01:05 New Realtime API voices: cedar, & marin
01:35 Upgrade the Twilio greeting with a Google voice
02:30 Find and choose a voice in Twilio docs
03:06 Update the model to gpt-realtime and remove beta header
03:43 Configure the Twilio number and webhook with ngrok
04:21 Live call demo with the AI assistant