Uploaded April 2026 | Updated September 2026, 2 weeks ago

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Dr. Kathryn Paige Harden and Dr. Andrew Huberman discuss the intersection of genetics, neuroscience, and personal responsibility, focusing on how biological factors—such as the MAOA gene and brain abnormalities—influence human behavior and the scientific challenges of defining moral and legal accountability.

Dr. Kathryn Paige Harden, PhD, is a psychologist, behavioral geneticist and professor of psychology at the University of Texas at Austin. Dr. Andrew Huberman is a tenured professor of neurobiology and ophthalmology at Stanford University School of Medicine and host of the Huberman Lab podcast.

Watch the full episode: youtu.be/rAbJC-Qaw7Q?si=D_ZSmtwX09iHF2_F
Show notes: go.hubermanlab.com/jKPoOgG

*Timestamps*
00:00 Moral Responsibility & Humans
00:49 Concept of Original Sin
02:31 Science & Human Behavior
03:48 Whitman Case & Brain Tumor
05:54 Amygdala Tumor Discovery
06:47 Genetics of Behavior
09:13 Balancing Science & Accountability

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Disclaimer & Disclosures: hubermanlab.com/disclaimer