Hepatitis B | Clinical Medicine @NinjaNerdOfficial
Hepatitis B | Clinical Medicine  @NinjaNerdOfficial
Uploaded June 2026 | Updated September 2026, 2 weeks ago
πŸ“š Premium Notes, Illustrations, Slides & Quiz for Hepatitis B: ninjanerd.org/lecture/hepatitis-b

Ninja Nerds!
In this lecture, Professor Zach Murphy breaks down Hepatitis B with a clear, high-yield approach focused on recognition, diagnosis, and management. This video builds a practical framework for understanding how Hepatitis B presents as both an acute and chronic infection and why it is one of the most clinically important viral hepatitides.

We begin with epidemiology and transmission, emphasizing bloodborne, sexual, and perinatal spread. Zach then walks through the pathophysiology, highlighting how the virus interacts with the immune system, leading to acute inflammation, potential chronic infection, and long-term complications.

Next, the lecture covers the clinical presentation and diagnosis, focusing on acute Hepatitis B symptoms, including fatigue, jaundice, and the classic immune-complex findings such as rash and arthralgias. You will learn the stepwise diagnostic approach using the Hepatitis B serology panel and how to interpret key markers to distinguish acute, chronic, and resolved infection.

The session then focuses on chronic Hepatitis B, including disease progression, risk of cirrhosis and hepatocellular carcinoma, and how to assess viral activity and infectivity using additional markers.

Finally, Zach reviews management and prevention, including indications for antiviral therapy, long-term monitoring, vaccination, and post-exposure prophylaxis.

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Table of Contents:
0:00 Lab
0:19 Etiology, Transmission and Pathophysiology of Hepatitis B
10:54 HDV Infection
29:57 Classic Findings of Prodrome
42:20 Classic Findings of Icteric Phase
48:04 Chronic Hepatitis B
51:00 Cirrhosis
54:56 Hepatocellular Carcinoma A
58:07 Acute Liver Failure
1:02:30 Extra Hepatic Manifestations
1:08:04 Diagnostic Approach to Hepatitis B
1:22:14 Treatment of Hepatitis B
1:28:16 Prevention of Hepatitis B
1:31:25 Comment, Like, SUBSCRIBE!

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