Uploaded October 2025 | Updated September 2026, 2 weeks ago
This week on The Weekly Shot, RMZ breaks down the biggest new science shaping how GLP-1 medications are redefining health — from the heart, to the immune system, to the brain itself.
🩺 1. Heart Health Breakthrough – A massive study from University College London shows semaglutide (Ozempic / Wegovy) lowers heart-attack and stroke risk even in people without diabetes — and the benefits go beyond weight loss.
🧬 2. Cancer Immunity Connection – Duke University researchers find that obesity suppresses immune response to cancer, but GLP-1s can help restore it — opening doors for future cancer therapies.
🌍 3. Eli Lilly Expands Globally – The company partners with India’s Cipla to launch GLP-1 drugs to new markets, signaling worldwide access and lower cost competition.
💸 4. The U.S. Cost Crunch – Insurance premiums and Medicaid budgets are straining under skyrocketing GLP-1 demand — and access gaps are widening.
🧠 5. Brain Mechanism Discovery – Northwestern scientists reveal how GLP-1 and GIP hormones suppress AgRP hunger neurons in the hypothalamus — showing that appetite control is neurochemistry, not willpower.
👶 6. Social Pressure & Postpartum Use – Growing numbers of new mothers report feeling pressured to use GLP-1s for post-pregnancy weight loss — even when it’s unsafe during breastfeeding.
00:00 Intro
00:42 Heart Health Breakthrough
02:17 Cancer Immunity Connection
03:13 Eli Lilly Expands In India
04:22 The U.S. Insurance Cost Crunch
05:24 Hunger Suppression Brain Mechanism Discovery
07:25 Social Pressure & Postpartum Use
08:00 Wrap-Up
Join RMZ for a deep dive into the science, the headlines, and the social impact of the GLP-1 revolution.
📺 New episodes weekly.
🎙️ Hosted by RMZ – creator of The Weekly Shot and Healthy MENtality.
Social Links
tiktok.com/@roundmoundofzepbound
instagram.com/roundmoundofzepbound
Items that I use on my journey (These are Amazon affiliate links from which I earn a small commission)
Scale:
Eufy P3 Smart Scale:
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Daily Supplements:
Bariatric Choice Once Daily Multivitamin
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Citracal Calcium Citrate & Calcium Carbonate w/Vitamin D
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LMNT Electrolyte Packs
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Manage Constipation:
Mag07 Natural Colon Cleanse & Detox
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Garden of Life Raw Organic Fiber Powder (9g)
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Migcopat 10g Fiber Gummies with Probiotics
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Amazon ClearLax (MiraLax)
amzn.to/3RLtClu
Ascuoli Pre and Probiotics (300 Billion CFU)
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Protein Goals:
Fairlife 30g Chocolate Protein Shake
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SEEQ Clear Whey Isolate
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The Only Bean Roasted Edamame Beans Variety 24 Pack
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The Only Bean Roasted Edamame Beans Single Flavor 10pk
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#zepbound #mounjaro #glp1 #weightloss #weightlossjourney #glp #tirzepatide #semaglutide #wegovy #ozempic #menshealth #TheWeeklyShot #HealthyMENtality #glp1news
This week on The Weekly Shot, RMZ breaks down the biggest new science shaping how GLP-1 medications are redefining health — from the heart, to the immune system, to the brain itself.
🩺 1. Heart Health Breakthrough – A massive study from University College London shows semaglutide (Ozempic / Wegovy) lowers heart-attack and stroke risk even in people without diabetes — and the benefits go beyond weight loss.
🧬 2. Cancer Immunity Connection – Duke University researchers find that obesity suppresses immune response to cancer, but GLP-1s can help restore it — opening doors for future cancer therapies.
🌍 3. Eli Lilly Expands Globally – The company partners with India’s Cipla to launch GLP-1 drugs to new markets, signaling worldwide access and lower cost competition.
💸 4. The U.S. Cost Crunch – Insurance premiums and Medicaid budgets are straining under skyrocketing GLP-1 demand — and access gaps are widening.
🧠 5. Brain Mechanism Discovery – Northwestern scientists reveal how GLP-1 and GIP hormones suppress AgRP hunger neurons in the hypothalamus — showing that appetite control is neurochemistry, not willpower.
👶 6. Social Pressure & Postpartum Use – Growing numbers of new mothers report feeling pressured to use GLP-1s for post-pregnancy weight loss — even when it’s unsafe during breastfeeding.
00:00 Intro
00:42 Heart Health Breakthrough
02:17 Cancer Immunity Connection
03:13 Eli Lilly Expands In India
04:22 The U.S. Insurance Cost Crunch
05:24 Hunger Suppression Brain Mechanism Discovery
07:25 Social Pressure & Postpartum Use
08:00 Wrap-Up
Join RMZ for a deep dive into the science, the headlines, and the social impact of the GLP-1 revolution.
📺 New episodes weekly.
🎙️ Hosted by RMZ – creator of The Weekly Shot and Healthy MENtality.
Social Links
tiktok.com/@roundmoundofzepbound
instagram.com/roundmoundofzepbound
Items that I use on my journey (These are Amazon affiliate links from which I earn a small commission)
Scale:
Eufy P3 Smart Scale:
amzn.to/41JOu0H
Daily Supplements:
Bariatric Choice Once Daily Multivitamin
amzn.to/45LN6Mr
Citracal Calcium Citrate & Calcium Carbonate w/Vitamin D
amzn.to/3RJ384c
LMNT Electrolyte Packs
amzn.to/3L1cILI
Manage Constipation:
Mag07 Natural Colon Cleanse & Detox
amzn.to/3XPvTzI
Garden of Life Raw Organic Fiber Powder (9g)
amzn.to/45tAnQA
Migcopat 10g Fiber Gummies with Probiotics
amzn.to/47llkJw
Amazon ClearLax (MiraLax)
amzn.to/3RLtClu
Ascuoli Pre and Probiotics (300 Billion CFU)
amzn.to/44bnxnA
Protein Goals:
Fairlife 30g Chocolate Protein Shake
amzn.to/4cHYQSn
SEEQ Clear Whey Isolate
amzn.to/4bqzZl0
The Only Bean Roasted Edamame Beans Variety 24 Pack
amzn.to/4bmkSt0
The Only Bean Roasted Edamame Beans Single Flavor 10pk
amzn.to/4ckcyvc
#zepbound #mounjaro #glp1 #weightloss #weightlossjourney #glp #tirzepatide #semaglutide #wegovy #ozempic #menshealth #TheWeeklyShot #HealthyMENtality #glp1news










