Uploaded March 2026 | Updated September 2026, 2 weeks ago
JAMA Article: jamanetwork.com/journals/jamaoncology/article-abstract/2840006
Donate to PCRI: pcri.org/donate
For more information, visit pcri.org
1:43 What does it mean for cancer to be called "cribriform"?
3:18 How can a patient confirm whether their cancer is cribriform or not?
4:11 Should all Gleason 4 patients get a second look to confirm whether their cancer is cribriform?
4:51 Can genetic tests detect cribriform cancer and does it grow in a different way?
6:35 What makes this a well-designed article?
8:55 How does the presence of cribriform cancer change one's treatment plans?
9:53 Does cribriform cancer demand a longer course of hormone therapy?
11:21 Is focal therapy still an option if cribriform cancer is present?
12:00 How many Gleason 4 patients have cribriform cancer?
12:26 Is it always worthwhile for Gleason 4 patients to seek a second opinion?
13:05 Does cribriform cancer affect how one weighs quality of life during treatment?
14:24 What is the optimal treatment for a Gleason 8 patient with cribriform cancer?
15:56 Alex’s conclusions
Don't know your stage? Take the quiz: visit prostatecancerstaging.org
To learn more about prostate cancer, visit pcri.org
Sign up for our newsletter here to receive the latest updates on prostate cancer and the PCRI: pcri.org/join
Who we are:
The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better-individualized care. Feel free to explore our website at pcri.org or contact our free helpline with any questions that you have at pcri.org/helpline. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors.
JAMA Article: jamanetwork.com/journals/jamaoncology/article-abstract/2840006
Donate to PCRI: pcri.org/donate
For more information, visit pcri.org
1:43 What does it mean for cancer to be called "cribriform"?
3:18 How can a patient confirm whether their cancer is cribriform or not?
4:11 Should all Gleason 4 patients get a second look to confirm whether their cancer is cribriform?
4:51 Can genetic tests detect cribriform cancer and does it grow in a different way?
6:35 What makes this a well-designed article?
8:55 How does the presence of cribriform cancer change one's treatment plans?
9:53 Does cribriform cancer demand a longer course of hormone therapy?
11:21 Is focal therapy still an option if cribriform cancer is present?
12:00 How many Gleason 4 patients have cribriform cancer?
12:26 Is it always worthwhile for Gleason 4 patients to seek a second opinion?
13:05 Does cribriform cancer affect how one weighs quality of life during treatment?
14:24 What is the optimal treatment for a Gleason 8 patient with cribriform cancer?
15:56 Alex’s conclusions
Don't know your stage? Take the quiz: visit prostatecancerstaging.org
To learn more about prostate cancer, visit pcri.org
Sign up for our newsletter here to receive the latest updates on prostate cancer and the PCRI: pcri.org/join
Who we are:
The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better-individualized care. Feel free to explore our website at pcri.org or contact our free helpline with any questions that you have at pcri.org/helpline. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors.
