Chubbyemu | Getting Some Gastric Juices Flowing 🌊 @chubbyemu | Uploaded 1 year ago | Updated 14 hours ago
Disorders of stomach secretion were revolutionized at the discovery of proton pump inhibitor therapy. For example, treatment of peptic ulcer disease before 1989 sometimes would be surgery. On a less severe scale, heartburn sometimes happen spontaneously, but is there something we could just change without any other intervention if it appears often? Maybe. PPI's profoundly increase stomach acid levels, so evidence for limiting proton pump activity as a way to control stomach acid is plausible, but we likely cannot and should not completely eliminate dietary potassium intake. However limiting it for a time may be help.
References:
Role of potassium in acid secretion ncbi.nlm.nih.gov/pmc/articles/PMC4622792
Gastric acid level of humans must decrease in the future
ncbi.nlm.nih.gov/pmc/articles/PMC7684463
The impact of proton pump inhibitors on the human gastrointestinal microbiome. ncbi.nlm.nih.gov/pmc/articles/PMC4254461
Diet and Gastroesophageal Reflux Disease asge.org/docs/default-source/about-asge/newsroom/doc-gerd_infographic_final.pdf
The effect and mechanism of action of capsaicin on gastric acid output.
pubmed.ncbi.nlm.nih.gov/19296048
The Physiology of the Gastric Parietal Cell. ncbi.nlm.nih.gov/pmc/articles/PMC7327232
Substituted benzimidazoles inhibit gastric acid secretion by blocking (H+ + K+) ATPase.
nature.com/articles/290159a0
Priming the (Proton) Pump. ncbi.nlm.nih.gov/pmc/articles/PMC4844173
A nonelectrogenic H+ pump in plasma membranes of hog stomach. jbc.org/article/S0021-9258(17)32907-1/pdf
#shorts #stomach #gas #candy
Disorders of stomach secretion were revolutionized at the discovery of proton pump inhibitor therapy. For example, treatment of peptic ulcer disease before 1989 sometimes would be surgery. On a less severe scale, heartburn sometimes happen spontaneously, but is there something we could just change without any other intervention if it appears often? Maybe. PPI's profoundly increase stomach acid levels, so evidence for limiting proton pump activity as a way to control stomach acid is plausible, but we likely cannot and should not completely eliminate dietary potassium intake. However limiting it for a time may be help.
References:
Role of potassium in acid secretion ncbi.nlm.nih.gov/pmc/articles/PMC4622792
Gastric acid level of humans must decrease in the future
ncbi.nlm.nih.gov/pmc/articles/PMC7684463
The impact of proton pump inhibitors on the human gastrointestinal microbiome. ncbi.nlm.nih.gov/pmc/articles/PMC4254461
Diet and Gastroesophageal Reflux Disease asge.org/docs/default-source/about-asge/newsroom/doc-gerd_infographic_final.pdf
The effect and mechanism of action of capsaicin on gastric acid output.
pubmed.ncbi.nlm.nih.gov/19296048
The Physiology of the Gastric Parietal Cell. ncbi.nlm.nih.gov/pmc/articles/PMC7327232
Substituted benzimidazoles inhibit gastric acid secretion by blocking (H+ + K+) ATPase.
nature.com/articles/290159a0
Priming the (Proton) Pump. ncbi.nlm.nih.gov/pmc/articles/PMC4844173
A nonelectrogenic H+ pump in plasma membranes of hog stomach. jbc.org/article/S0021-9258(17)32907-1/pdf
#shorts #stomach #gas #candy
