Uploaded June 2026 | Updated September 2026, 3 weeks ago

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Stephen Wolfram hosts an unscripted Ask Me Anything about the future of science and technology for all ages.

Originally livestreamed at: twitch.tv/stephen_wolfram

If you missed the original livestream of this episode, feel free to submit a question you would like Stephen to answer in a future Q&A livestream here: https://wolfr.am/12cczmv5J

00:00 Start stream
00:13 Could there be a point where technology becomes so personalized that two people effectively live in different realities?
11:10 Will AI agents have their own sovereign counties?
20:31 Will the movie Wall-E become real because AI? Humans who are conditioned to do nothing
24:30 Do you expect the next breakthrough to come from a person, a team, or an AI-assisted computational process?
29:11 Which is the bigger bottleneck for progress: lack of knowledge, lack of computation, or lack of conceptual frameworks?
34:41 Where do you think we stand in terms of progress in human longevity?
49:09 ​​In a sense, with knowledge work, strife has moved from physical exertion to mental exertion/stress. Is this expected to continue and what form are related diseases expected to get? (we've heard of AI psychosis for example)
53:43 More about human longevity
57:44 Maybe we are just the vehicle for mitochondria, they are the persistent information of life.
59:19 If whole-brain emulation succeeds, what would be the bigger shock to science: discovering that minds are computable, or discovering that personal identity is not what we thought it was?
1:02:48 ​If you linked two brains together with wires, would it be one mind or two?
1:05:47 Regarding the recent AI-assisted progress on an Erdős problem, what will determine whether we trust those results, and how common do you think this will become in the future?
1:16:33 End stream

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