Uploaded April 2019 | Updated September 2026, 2 weeks ago

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For Michael Caligiuri and @theohiostateuniversity we have created a series of animations on the functioning and potential of Fc Bridged Cell-mediated Cytotoxicity.

CONTENT
00:00 Antibody
00:34 Herpes Simplex Virus 1 Infection
00:55 Immune Response
01:11 Viral Infected Cell Membrane
01:33 Antibody Immune Response
02:10 NK Cell bind to 2 Antibodies on the Cell Surface
02:29 Comparing Different Binding Scenarios
02:49 Antibody's Immune Cell Binding Initiation
03:31 Endogenous Fc Binding Protein(s)
03:48 Manufactured Therapeutic Antibodies
03:58 Manufactured Antibody Induced Inflamation
04:19 Antibody
04:33 Null-IgG Fragment
04:55 Glioblastoma in vitro
05:19 Glioblastoma in vivo
05:28 Oncolyctic HSV1 Treated Glioblastoma
05:40 Fc Bridged Cellular Cytotoxicity
05:49 Block Fc Bridging
06:07 Innate Immune Response Blocked

SOURCE
https://www.osu.edu/
cell.com/immunity/fulltext/S1074-7613(17)30279-0

#biology #medical #health

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