Ep 354 - All About Central or Systemic Fatigue @IronCulturePodcast
Ep 354 - All About Central or Systemic Fatigue  @IronCulturePodcast
Uploaded November 2025 | Updated September 2026, 1 day ago
In this episode, Eric Trexler and Eric Helms begin by discussing Helms' competition updates and the sad state of affairs in academic publishing (that is, scientific journals). Eric and Eric then take a deep dive into the complexities of central fatigue, systemic fatigue, the accumulation of fatigue, and deloading strategies. The conversation emphasizes the importance of personalized approaches to recovery and the role of intensity in achieving hypertrophy. They close by discussing misconceptions surrounding fatigue management in bodybuilding, the necessity of understanding the mechanisms behind muscle growth, and how current trends in "evidence-based content" are leading new lifters astray.

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Chapters
0:00 Introduction and Helms Bodybuilding Updates
5:17 A New Threat to the Integrity of PhDs
8:25 Academic publishing (i.e., scientific journals) is so over
26:52 Understanding Systemic and Central Fatigue
41:31 Holistic Approaches to Deloading and Fatigue Management
1:00:42 Tiger Balm and Icy Hot
1:08:04 Cardio (To Build Work Capacity for Bodybuilding)
1:15:41 Current trends in "evidence-based content" are leading new lifters astray
Ep 354 - All About Central or Systemic FatigueEp 387 - Energy Cost of Building MuscleEp 389 - What the Erics Actually DoEp 314 - Science Is Broken (But Fixable)Ep 385 - Do Studies on Untrained Lifters Apply to Trained Lifters?Ep 290 -  Is Caffeine An Overrated Supplement For Lifters?Ep 379 - Behind the Scenes (Iron Culture Documentary) ft. Omar IsufEp 318 - Resistance Training as a Fat Loss Tool (ft. Dr. Mike Ormsbee)Ep 305 - What is Strength? (w/Drs. Adrian Kind, Conor Heffernan & Walter Veit)Ep. 220- The Lifting Stones of Ireland (ft. David Keohan)Ep. 280- Key Qualities of Good CoachesEp 321 - Are You Really As Hydrated As You Think?
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Ep 354 - All About "Central" or "Systemic" Fatigue

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