Ep 354 - All About Central or Systemic Fatigue @MASSResearchReview
Ep 354 - All About Central or Systemic Fatigue  @MASSResearchReview
Uploaded November 2025 | Updated September 2026, 6 hours ago
In this episode, Eric Trexler and Eric Helms begin by discussing Helms' competition updates and the sad state of affairs in academic publishing (that is, scientific journals). Eric and Eric then take a deep dive into the complexities of central fatigue, systemic fatigue, the accumulation of fatigue, and deloading strategies. The conversation emphasizes the importance of personalized approaches to recovery and the role of intensity in achieving hypertrophy. They close by discussing misconceptions surrounding fatigue management in bodybuilding, the necessity of understanding the mechanisms behind muscle growth, and how current trends in "evidence-based content" are leading new lifters astray.

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Chapters
0:00 Introduction and Helms Bodybuilding Updates
5:17 A New Threat to the Integrity of PhDs
8:25 Academic publishing (i.e., scientific journals) is so over
26:52 Understanding Systemic and Central Fatigue
41:31 Holistic Approaches to Deloading and Fatigue Management
1:00:42 Tiger Balm and Icy Hot
1:08:04 Cardio (To Build Work Capacity for Bodybuilding)
1:15:41 Current trends in "evidence-based content" are leading new lifters astray
Ep 354 - All About Central or Systemic FatigueMASS Office Hours Episode 31 (Preloads for Satiety + Q&A)MASS Office Hours Episode 11 (The Science of Muscle Growth w/ Dr. Brad Schoenfeld)Ep 387 - Energy Cost of Building MuscleEp 341 - Unpacking Individual Responses to Training VolumeMASS Office Hours Episode 44 (Flexible Training Templates + Q&A)Ep 308 - The Future of Natural Bodybuilding (w/ WNBF Pros Alberto Nuñez and Steff Noble)MASS Office Hours Episode 9 (Muscular Fatigue, Sleep Quality, Boosting Metabolism)Ep 370 - Calories: Labels vs RealityEp 337 - Is There A Crisis In Exercise Science?Ep 343 - Q&A: Is Collagen Useful?Ep 345 - Hot Topics in Fitness (ft. Dr. Lauren Colenso-Semple)
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Ep 354 - All About "Central" or "Systemic" Fatigue

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