Ep 333 - Are High-Protein Diets Really Harmless? @MASSResearchReview
Ep 333 - Are High-Protein Diets Really Harmless?  @MASSResearchReview
Uploaded June 2025 | Updated September 2026, 30 minutes ago
In this episode of Iron Culture, Dr. Eric Helms talks about his forthcoming article in the MASS Research Review covering the purported harms of high-protein diets. This isn’t your typical oversimplified dunk-fest that readily dismisses concerns about high-protein diets. Instead, Helms reviews a thorough paper that reviews common concerns in detail and assessed their plausibility in an objective manner. The claims include:

Claim 1 – protein reduces lifespan
Claim 2 – protein makes bones weaker
Claim 3 – protein harms kidneys
Claim 4 – protein causes diabetes

After that, Dr. Eric Trexler discusses a recent Instagram thread that pulled him into arguments against his will. The post was about his recent article on ketogenic diets and seed oils – two topics that are always bound to attract some controversy and heated debate. This conversation discusses the strengths and limitations of different types of scientific research and also touches on bias, objectivity, and the process of seeking the truth with an open mind.

Time stamps:
0:00 Intro
3:00 Helms’ new article about the purported harms of high-protein diets
19:25 Claim 1 – protein reduces lifespan
27:48 Claim 2 – protein makes bones weaker
43:38 Claim 3 – protein harms kidneys
50:53 Claim 4 – protein causes diabetes
57:22 Trex’s social media beefs – keto and seed oils
1:03:40 Types of observational studies
1:08:35 Seeking truth versus defending biases
1:17:32 Limitations versus fatal flaws
1:24:19 Limitations of RCTs (randomized controlled trials)
1:32:23 Wrapping up
Ep 333 - Are High-Protein Diets Really Harmless?Ep 386 - Sleep, Hypertrophy, and CreatineMASS Office Hours Episode 37 (Exercise Order for Strength and Hypertrophy)MASS Office Hours Episode 26 (Progressive Overload Strategies + Q&A)Ep 383 - Q&A: Imbalances, Fatigue, & REDsEp 320 - Myths Versus Theories in Exercise Science (ft. James Steele)Ep 376 - Weight Loss ResistanceEp 346 - Helms Updates + Q&AMASS Office Hours Episode 13 (Periodization, Behavior Change, Exercise vs. Fitness)Ep 306 - Mental Health, Physique Sports, and Fitness Coaching (ft. Laurin Conlin)Ep 321 - Are You Really As Hydrated As You Think?Ep 339 - ECA Stack & Yohimbine
MASS Research Review |

Ep 333 - Are High-Protein Diets Really Harmless?

SHARE TO X SHARE TO REDDIT SHARE TO FACEBOOK WALLPAPER