Uploaded October 2024 | Updated September 2026, 4 days ago
In this Iron Culture/Sports Nutrition Association/Sigma Nutrition Radio crossover episode, host Eric Trexler is joined by co-host Danny Lennon and guest Dr. Shawn Arent. Dr. Arent is a professor and department chair at the University of South Carolina with a wealth of knowledge and research experience pertaining to nutritional strategies and supplements purported to support brain health and function. In this meeting of the minds, Eric, Danny, and Dr. Arent discuss the brain-related effects of carbohydrate, amino acids, caffeine (and caffeine-related substances), theanine, nicotine, fish oil, creatine, and much more. If you’re interested in preserving the health and function of your brain, listening to this episode is certainly a smart decision.
00:00 Introduction to another crossover episode and Dr Shawn Arent
03:20 Defining cognitive performance and function
07:48 The acute effects of carbohydrates and caffeine on fatigue
13:01 Carbohydrate mouth rinsing and glycogen depletion (and are bodybuilders athletes?)
26:15 The (non-linear) glycogen utilisation response to exercise
29:53 The role of protein (EAAs and BCAAs) on cognitive function
Daivs 1999 Effects of branched-chain amino acids and carbohydrate on fatigue during intermittent, high-intensity running pubmed.ncbi.nlm.nih.gov/10452228
36:06 Caffeine dose-response relationship on cognition
40:50 Caffeine timing and dosing strategies
51:38 Optimisation and thinking outside the box to minimise the effects of caffeine on sleep
55:18 Other (interesting) supplements with less evidence
1:01:28 Nicotine and sports culture
1:08:52 Supplementation for brain health and recommendations/protocols for TBIs
1:21:22 Closing out with some final take homes
In this Iron Culture/Sports Nutrition Association/Sigma Nutrition Radio crossover episode, host Eric Trexler is joined by co-host Danny Lennon and guest Dr. Shawn Arent. Dr. Arent is a professor and department chair at the University of South Carolina with a wealth of knowledge and research experience pertaining to nutritional strategies and supplements purported to support brain health and function. In this meeting of the minds, Eric, Danny, and Dr. Arent discuss the brain-related effects of carbohydrate, amino acids, caffeine (and caffeine-related substances), theanine, nicotine, fish oil, creatine, and much more. If you’re interested in preserving the health and function of your brain, listening to this episode is certainly a smart decision.
00:00 Introduction to another crossover episode and Dr Shawn Arent
03:20 Defining cognitive performance and function
07:48 The acute effects of carbohydrates and caffeine on fatigue
13:01 Carbohydrate mouth rinsing and glycogen depletion (and are bodybuilders athletes?)
26:15 The (non-linear) glycogen utilisation response to exercise
29:53 The role of protein (EAAs and BCAAs) on cognitive function
Daivs 1999 Effects of branched-chain amino acids and carbohydrate on fatigue during intermittent, high-intensity running pubmed.ncbi.nlm.nih.gov/10452228
36:06 Caffeine dose-response relationship on cognition
40:50 Caffeine timing and dosing strategies
51:38 Optimisation and thinking outside the box to minimise the effects of caffeine on sleep
55:18 Other (interesting) supplements with less evidence
1:01:28 Nicotine and sports culture
1:08:52 Supplementation for brain health and recommendations/protocols for TBIs
1:21:22 Closing out with some final take homes
