Uploaded July 2018 | Updated September 2026, 1 hour ago
Duncan Hines (March 26, 1880 – March 15, 1959) was an American pioneer of restaurant ratings for travelers. He is best known today for the brand of food products that bears his name.
Duncan Hines (March 26, 1880 – March 15, 1959) was an American pioneer of restaurant ratings for travelers. He is best known today for the brand of food products that bears his name.
![Nuprin - Tv commercial - nupe it - 1995
Ibuprofen
(RS)-Ibuprofen Structural Formula V1.svg
(R)-ibuprofen
Clinical data
Pronunciation /ˈaɪbjuːproʊfɛn/, /aɪbjuːˈproʊfən/, EYE-bew-PROH-fən
Trade names Advil, Motrin, Nurofen, others
Synonyms isobutylphenylpropionic acid
AHFS/Drugs.com Monograph
MedlinePlus a682159
License data
EU EMA: by INN
US FDA: Ibuprofen
Pregnancy
category
AU: C
US: C (Risk not ruled out)
D (US) at ≥30 weeks of gestation, due to the potential for premature closure of the ductus arteriosus
Routes of
administration by mouth, rectal, topical, and intravenous
ATC code
C01EB16 (WHO) G02CC01 (WHO) M01AE01 (WHO) M02AA13 (WHO) R02AX02 (WHO)
Legal status
Legal status
AU: OTC
CA: OTC
UK: General sales list (GSL, OTC)
US: OTC (Rx-only at higher doses)
Pharmacokinetic data
Bioavailability 80–100% (by mouth),[2] 87% (rectal)
Protein binding 98%[1]
Metabolism Liver (CYP2C9)[1]
Onset of action 30 min[3]
Elimination half-life 2–4 h[4]
Excretion Urine (95%)[1][5]
Identifiers
IUPAC name[show]
CAS Number
15687-27-1 Yes
PubChem CID
3672
IUPHAR/BPS
2713
DrugBank
DB01050 Yes
ChemSpider
3544 Yes
UNII
WK2XYI10QM
KEGG
D00126 Yes
ChEBI
CHEBI:5855 Yes
ChEMBL
CHEMBL521 Yes
PDB ligand
IBP (PDBe, RCSB PDB)
ECHA InfoCard 100.036.152 Edit this at Wikidata
Chemical and physical data
Formula C13H18O2
Molar mass 206.29 g/mol
3D model (JSmol)
Interactive image
Chirality Racemic mixture
Density 1.03 g/ml g/cm3
Melting point 75 to 78 °C (167 to 172 °F)
Boiling point 157 °C (315 °F)
Solubility in water 0.021 mg/mL (20 °C)
SMILES[show]
InChI[show]
(verify)
Ibuprofen is a medication in the nonsteroidal anti-inflammatory drug (NSAID) class that is used for treating pain, fever, and inflammation.[6] This includes painful menstrual periods, migraines, and rheumatoid arthritis.[6] It may also be used to close a patent ductus arteriosus in a premature baby.[6] It can be used by mouth or intravenously.[6] It typically begins working within an hour. Nuprin - Tv commercial - nupe it - 1995](https://i.ytimg.com/vi/m7H-qSJDltk/mqdefault.jpg)


![Magnavox picture in picture tv commercial - 1988
Magnavox
Magnavox Logo.svg
Type
Subsidiary
Industry Consumer electronics
Founded 1917; 101 years ago
Napa, California, U.S.
Founder Edwin Pridham
Peter L. Jensen
Headquarters Knoxville, Tennessee, USA
Products Odyssey (video game console), TVs, speakers, Blu-ray and DVD players, dehumidifiers, heaters, air conditioners, headphones, batteries
Parent Philips
Website magnavox.com
Magnavox brand on a vintage amplifier
Magnavox (Latin for great voice) (stylized as MAGNAVOX) is an American electronics company founded in the United States. Today it is a subsidiary of electronics corporation Philips.
The predecessor to Magnavox was founded in 1911 by Edwin Pridham and Peter L. Jensen, co-inventors of the moving-coil loudspeaker at their lab in Napa, California under United States Patent number 1,105,924 for telephone receivers.[1] Six decades later, Magnavox produced the Odyssey, the worlds first home video game console toy.
Magnavox is the brand name worn by a line of products now made by Funai under license from trademark owner Philips.[2 Magnavox picture in picture tv commercial - 1988](https://i.ytimg.com/vi/mH6pq9SjCNY/mqdefault.jpg)
![Northwest Airlines - Tv commercial - 1987
Northwest Airlines Corp. (often abbreviated as NWA and stylized as nwa) was a major United States airline founded in 1926 and absorbed into Delta Air Lines, Inc. by a merger. The merger, approved on October 29, 2008, made Delta the largest airline in the world until the American Airlines-US Airways merger on December 9, 2013.[3][4] Northwest continued to operate under its own name and brand until the integration of the carriers was completed on January 31, 2010.[5] Northwest Airlines - Tv commercial - 1987](https://i.ytimg.com/vi/mgASwoZUxrU/mqdefault.jpg)
![WOMETCO cable tv promo - 1996
Wometco was founded in 1925 as the Wolfson-Meyer Theater Company, a movie theatre chain based in Miami. The companys co-founders were brothers-in-law Mitchell Wolfson (1900–1983) and Sidney Meyer.[1] The first movie theater opened by the firm was the Capitol Theater in downtown Miami, built in 1926. Over the years the company built up the largest chain of movie theaters in South Florida, and adopted the portmanteau name of Wometco sometime in the 1950s.
In 1949 Wometco moved into broadcasting with the founding of WTVJ in Miami, Floridas first television station. The station signed on in March 1949 from studios inside the Capitol Theatre, which was renovated for television. Wometco purchased WLOS-AM-FM-TV in Asheville, North Carolina in 1958, and KVOS-TV in Bellingham, Washington was added in 1961. In 1976 Wometco bought WTVG (now WFUT-TV) in Newark, New Jersey, and in 1978 acquired WZZM-TV in Grand Rapids, Michigan. In 1977 Wometco launched a nationwide, over-the-air subscription television service called Wometco Home Theater, using WTVG as its flagship station.
Wometco expanded its non-entertainment holdings in 1955, with the opening of the Miami Seaquarium. It bought the Blue Circle hamburger chain, based in Knoxville, Tennessee in 1966, but sold it in 1974. WOMETCO cable tv promo - 1996](https://i.ytimg.com/vi/mlaqtuDJfT8/mqdefault.jpg)

![Neutrogena oil free acne wash - Jennifer Freeman - Tv commercial - 2003
Neutrogena is an American brand of skin care, hair care and cosmetics, that is headquartered in Los Angeles, California.[1] According to product advertising at their website, Neutrogena products are distributed in more than 70 countries. Neutrogena was founded in 1930 by Emanuel Stolaroff, and was originally a cosmetics company named Natone. It is now part of the US-based Johnson & Johnson conglomerate, which bought the independent company in 1994.[2] Neutrogena oil free acne wash - Jennifer Freeman - Tv commercial - 2003](https://i.ytimg.com/vi/oGZK8NHMgvg/mqdefault.jpg)

![OIl of Olay 2 in 1 - Tv commercial - 1995
Olay, previously Oil of Olay or Oil of Ulay, is an American skin care line. It is one of Procter & Gambles multibillion-dollar brands. For the 2009 fiscal year, which ended on June 30, Olay accounted for an estimated $2.8 billion of P&Gs $79 billion in revenue.[1] OIl of Olay 2 in 1 - Tv commercial - 1995](https://i.ytimg.com/vi/ouTPYzbRYMM/mqdefault.jpg)
