Nutrition Made Simple! | Does Red Yeast Rice work? | Cholesterol-lowering supplements @NutritionMadeSimple | Uploaded November 2022 | Updated October 2024, 7 minutes ago.
Do cholesterol-lowering supplements like red yeast rice and phytosterols work? Are they safe? Little-known aspects of supplements, doses and safety concerns.
A new trial compared a statin to several supplements. Rosuvastatin vs phytosterols vs red yeast rice
low dose of statin, 5mg. 1.6mg sterols, 2.4mg red yeast rice.
the active ingredients in red yeast rice are called monacolins, the main one being monacolin K.
analysis of trials using red yeast rice. lowered LDLcholesterol by 40pts. red yeast rice not significantly different from statin
not all trials report amount of monacolin K in the supplements. effect of supplements varies depending on where we get our bottle.
phytosterols: analysis of trials shows phytosterols lowers LDLc by ~8-10% So phytosterols probably do have a cholesterol-lowering effect its just mild
Quick caveat regarding phytosterols: some people are sterol hyperabsorbers in the intestine, and for those people, phytosterol supplements are not a good idea. Another option is a stanol, which also lowers cholesterol and doesnt get absorbed
caveat with supplements: safety. Most available data with red yeast rice suggests low side effects. trial for red yeast rice looked at risk.
Connect with me:
Facebook: facebook.com/DrGilCarvalho
Twitter: twitter.com/NutritionMadeS3
Animations: Even Topland @toplandmedia
References:
1-jacc.org/doi/epdf/10.1016/j.jacc.2022.10.013
2jamanetwork.com/journals/jamainternalmedicine/fullarticle/226109
3-ncbi.nlm.nih.gov/pmc/articles/PMC5613479
4-sciencedirect.com/science/article/pii/S0021915015002221
5-link.springer.com/article/10.1186/1749-8546-1-4
6-sciencedirect.com/science/article/pii/S0021915013004875
7-agsjournals.onlinelibrary.wiley.com/doi/full/10.1111/j.1532-5415.2007.01230.x
8-https://ir.nctu.edu.tw/bitstream/11536/8558/1/000257721400029.pdf
academic.oup.com/eurheartjsupp/article/21/Supplement_B/B71/5422925
Position paper: academic.oup.com/nutritionreviews/article/75/9/731/4065280
Disclaimer: The contents of this video are for informational purposes only and are not intended to be medical advice, diagnosis, or treatment, nor to replace medical care. The information presented herein is accurate and conforms to the available scientific evidence to the best of the author's knowledge as of the time of posting. Always seek the advice of your physician or other qualified health provider with any questions regarding any medical condition. Never disregard professional medical advice or delay seeking it because of information contained in Nutrition Made Simple!.
#NutritionMadeSimple #GilCarvalho
0:00 New trial: cholesterol-lowering supplements
1:12 Big Pharma funding?
2:22 Do supplements work?
3:08 Can we trust supplements labels?
4:30 Red Yeast Rice
6:37 Phytosterols
7:51 Safety
8:20 Cardiovascular Risk
9:44 Legal Battles
10:35 My approach to cholesterol-lowering
Do cholesterol-lowering supplements like red yeast rice and phytosterols work? Are they safe? Little-known aspects of supplements, doses and safety concerns.
A new trial compared a statin to several supplements. Rosuvastatin vs phytosterols vs red yeast rice
low dose of statin, 5mg. 1.6mg sterols, 2.4mg red yeast rice.
the active ingredients in red yeast rice are called monacolins, the main one being monacolin K.
analysis of trials using red yeast rice. lowered LDLcholesterol by 40pts. red yeast rice not significantly different from statin
not all trials report amount of monacolin K in the supplements. effect of supplements varies depending on where we get our bottle.
phytosterols: analysis of trials shows phytosterols lowers LDLc by ~8-10% So phytosterols probably do have a cholesterol-lowering effect its just mild
Quick caveat regarding phytosterols: some people are sterol hyperabsorbers in the intestine, and for those people, phytosterol supplements are not a good idea. Another option is a stanol, which also lowers cholesterol and doesnt get absorbed
caveat with supplements: safety. Most available data with red yeast rice suggests low side effects. trial for red yeast rice looked at risk.
Connect with me:
Facebook: facebook.com/DrGilCarvalho
Twitter: twitter.com/NutritionMadeS3
Animations: Even Topland @toplandmedia
References:
1-jacc.org/doi/epdf/10.1016/j.jacc.2022.10.013
2jamanetwork.com/journals/jamainternalmedicine/fullarticle/226109
3-ncbi.nlm.nih.gov/pmc/articles/PMC5613479
4-sciencedirect.com/science/article/pii/S0021915015002221
5-link.springer.com/article/10.1186/1749-8546-1-4
6-sciencedirect.com/science/article/pii/S0021915013004875
7-agsjournals.onlinelibrary.wiley.com/doi/full/10.1111/j.1532-5415.2007.01230.x
8-https://ir.nctu.edu.tw/bitstream/11536/8558/1/000257721400029.pdf
academic.oup.com/eurheartjsupp/article/21/Supplement_B/B71/5422925
Position paper: academic.oup.com/nutritionreviews/article/75/9/731/4065280
Disclaimer: The contents of this video are for informational purposes only and are not intended to be medical advice, diagnosis, or treatment, nor to replace medical care. The information presented herein is accurate and conforms to the available scientific evidence to the best of the author's knowledge as of the time of posting. Always seek the advice of your physician or other qualified health provider with any questions regarding any medical condition. Never disregard professional medical advice or delay seeking it because of information contained in Nutrition Made Simple!.
#NutritionMadeSimple #GilCarvalho
0:00 New trial: cholesterol-lowering supplements
1:12 Big Pharma funding?
2:22 Do supplements work?
3:08 Can we trust supplements labels?
4:30 Red Yeast Rice
6:37 Phytosterols
7:51 Safety
8:20 Cardiovascular Risk
9:44 Legal Battles
10:35 My approach to cholesterol-lowering
