A Skeptical Human | Does CBD Oil Work For Anxiety? @ASkepticalHumanOnYouTube | Uploaded December 2019 | Updated October 2024, 5 hours ago.
Many claim that CBD cures or reduces anxiety, and here I examine the lines of evidence used to support this view. Personal anecdotes aren't good enough because of the placebo effect and other confounding factors. Animal studies don't necessarily map onto humans, and showing that CBD counteracts the effects of THC isn't the same as proving that it has standalone effects of its own. The clinical trials do show that CBD reduces anxiety, but where you can measure the effect, it's quite small. More studies are needed with larger sample sizes to better understand its effects, and for several reasons we should be cautious and skeptical of the current CBD market.
Support my videos on Patreon!: patreon.com/askepticalhuman
Merch store!: shopaskepticalhuman.com
Follow me on Twitter: twitter.com/aSkepticalHuman
Text or audio version of this content is available on my website: askepticalhuman.com/science/2019/12/25/is-cbd-oil-just-snake-oil-pt-1-anxiety
Thumbnail photo: STAPAW/PxHere
References:
LiveScience on CBD receptors in brain -- livescience.com/65811-what-is-cbd.html
ANIMAL STUDIES:
Guimarães et al 1990 -- ncbi.nlm.nih.gov/pubmed/1969666
MazeEngineers on elevated plus maze -- youtube.com/watch?v=Fn8WRyufcpI
Linares et al 2019 -- http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462019000100009&lng=en&tlng=en
CBD vs THC STUDIES:
Zuardi et al 1992 -- pdfs.semanticscholar.org/21fb/e9e48b675bc56a484614662c42357213b179.pdf
Karniol et al 1974 -- ncbi.nlm.nih.gov/pubmed/4609777
Dalton et al 1976 -- ncbi.nlm.nih.gov/pubmed/770048
Hollister & Gillespie 1975 -- ncbi.nlm.nih.gov/pubmed/1097148
Naloxone vs opiates -- harmreduction.org/issues/overdose-prevention/overview/overdose-basics/understanding-naloxone
STUDIES ON CBD vs ANXIETY IN HUMANS:
Bergamaschi et al 2011 -- ncbi.nlm.nih.gov/pmc/articles/PMC3079847
Linares et al 2019 -- http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462019000100009&lng=en&tlng=en
Zuardi et al 1993 -- ncbi.nlm.nih.gov/pubmed/22290374
Crippa et al 2011 -- ncbi.nlm.nih.gov/pubmed/20829306
Laura Sanders on the CBD market -- sciencenews.org/article/cbd-product-boom-science-research-hemp-marijuana
Thank you all for watching and listening! These videos take a lot of time and work to produce, so please support me on Patreon!
Many claim that CBD cures or reduces anxiety, and here I examine the lines of evidence used to support this view. Personal anecdotes aren't good enough because of the placebo effect and other confounding factors. Animal studies don't necessarily map onto humans, and showing that CBD counteracts the effects of THC isn't the same as proving that it has standalone effects of its own. The clinical trials do show that CBD reduces anxiety, but where you can measure the effect, it's quite small. More studies are needed with larger sample sizes to better understand its effects, and for several reasons we should be cautious and skeptical of the current CBD market.
Support my videos on Patreon!: patreon.com/askepticalhuman
Merch store!: shopaskepticalhuman.com
Follow me on Twitter: twitter.com/aSkepticalHuman
Text or audio version of this content is available on my website: askepticalhuman.com/science/2019/12/25/is-cbd-oil-just-snake-oil-pt-1-anxiety
Thumbnail photo: STAPAW/PxHere
References:
LiveScience on CBD receptors in brain -- livescience.com/65811-what-is-cbd.html
ANIMAL STUDIES:
Guimarães et al 1990 -- ncbi.nlm.nih.gov/pubmed/1969666
MazeEngineers on elevated plus maze -- youtube.com/watch?v=Fn8WRyufcpI
Linares et al 2019 -- http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462019000100009&lng=en&tlng=en
CBD vs THC STUDIES:
Zuardi et al 1992 -- pdfs.semanticscholar.org/21fb/e9e48b675bc56a484614662c42357213b179.pdf
Karniol et al 1974 -- ncbi.nlm.nih.gov/pubmed/4609777
Dalton et al 1976 -- ncbi.nlm.nih.gov/pubmed/770048
Hollister & Gillespie 1975 -- ncbi.nlm.nih.gov/pubmed/1097148
Naloxone vs opiates -- harmreduction.org/issues/overdose-prevention/overview/overdose-basics/understanding-naloxone
STUDIES ON CBD vs ANXIETY IN HUMANS:
Bergamaschi et al 2011 -- ncbi.nlm.nih.gov/pmc/articles/PMC3079847
Linares et al 2019 -- http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462019000100009&lng=en&tlng=en
Zuardi et al 1993 -- ncbi.nlm.nih.gov/pubmed/22290374
Crippa et al 2011 -- ncbi.nlm.nih.gov/pubmed/20829306
Laura Sanders on the CBD market -- sciencenews.org/article/cbd-product-boom-science-research-hemp-marijuana
Thank you all for watching and listening! These videos take a lot of time and work to produce, so please support me on Patreon!
