Science, Technology & the Future | Denis Odinokov - Conquering Cross-Linking for Biomedical Longevity @scfu | Uploaded August 2019 | Updated October 2024, 6 hours ago.
Cells are held together by special linking proteins. When too many cross-links form between cells in a tissue, the tissue can lose its elasticity and cause problems including arteriosclerosis, presbyopia and weakened skin texture. These are chemical bonds between structures that are part of the body, but not within a cell. In senescent people many of these become brittle and weak.


Introduction to Denis' writing/research here: blog.singularitynet.io/the-impact-of-extracellular-matrix-proteins-cross-linking-on-the-aging-process-b7553d375744
"The Impact of Extracellular Matrix Proteins Cross-linking on the Aging Process"

Biomedical Longevity - Conquering Crosslinking of the Extracellular Matrix!
SENS proposes to further develop small-molecular drugs and enzymes to break links caused by sugar-bonding, known as advanced glycation endproducts, and other common forms of chemical linking.

GlycoSENS : en.wikipedia.org/wiki/Strategies_for_Engineered_Negligible_Senescence#Extracellular_crosslinks%E2%80%94GlycoSENS

Scifuture blog post: scifuture.org/denis-odinokov-conquering-cross-linking-for-biomedical-longevity

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