Uploaded October 2018 | Updated September 2026, 2 weeks ago
Part 1:
youtube.com/watch?v=Q9mL7MqJjII
Discord Invite (all studies can be found here):
discord.gg/jgqKjUB
Ask yourself:
youtube.com/askyourself
Original Video:
youtube.com/watch?v=ULtqCBimr6U
Thanks to Meg for these timestamps:
0:24 Introduction
4:13 Response to Kahn’s comments
14:28 The confounding factors that were controlled for in the Epic Oxford Study and the Health Food Shoppers Study from part 1
21:00 Diet switching in the Epic Oxford / OVS studies
38:40 Isaac and Avi summarize the last 25 mins
39:18 Resuming the podcast
41:04 TMAO (Trimethylamine N-oxide) argument starts to unfold
42:54 The fibrosis of kidneys in relation to TMAO
46:21 Explaining what TMAO is and why it is a bad argument
54:10 Kahn pointing out Kresser’s inconsistency on epidemiological studies
59:13 Kresser’s TMAO graph
1:05:51 TMAO and the gut microbiome
1:07:15 Fasting TMAO levels
1:12:00 Kahn not addressing the study
1:19:00 Dioxins in fish
1:21:53 Old tho
1:24:00 There is still an ethical problem with eating fish
1:25:07 Kresser speculating on which diets change microbiome composition
1:28:16 High fasting TMAO levels are what is correlated with atherosclerosis
1:32:50 Debate advice on staying out of situations that make you look bad
1:33:41 Thoughts on nutritional reductionism
1:40:07 Kahn’s speculations
1:46:35 The Yazdekhasti paper
1:48:22 Cat studies meme
1:51:20 Fish makes diabetes tho
1:58:10 Final point addressing TMAO
2:13:32 Bad ethical arguments for veganism
2:15:44 Responding to the chat’s objections, and reading through and commenting on the l-carnitine study
2:34:22 Importance of the evidence hierarchy
2:51:11 Summary of Avi’s response to the l-carnitine study
2:55:20 Resuming the podcast
2:59:48 Kahn derails from TMAO to diabetes and general health as a result of fish consumption
3:04:06 Methionine tho
3:08:21 Glycine tho
3:08:53 Fish Consumption and Incidence of Diabetes Meta-analysis
3:18:20 Nutritional black box tho
3:21:05 Meat allergy lone star tick
3:23:25 Rogan’s bias?
3:27:57 Rogan’s interest in the lone star tick
3:28:48 Glyphosate tho
3:29:56 Statistics and astrological signs tho
3:37:18 Isaac summarises Kresser’s medical sophistry
3:38:47 Relative risk tho
3:39:40 Association between maternal gluten intake and type 1 diabetes in offspring (Gluten tho)
3:44:23 Assertions that there could be other confounding factors that were not controlled for in the studies
3:52:50 B12 tho
4:04:40 Humans can get B12 from dirt and water myth
4:06:46 Things that vegans need to stop saying
4:11:41 “Vegans living without supplementation are not living a healthy life”
4:13:10 Kahn demonstrates his simple B12 solution
4:15:49 “Diets do not need to be supplement free” (Natural tho)
4:19:00 Kahn demonstrates how easy supplementing is once more
4:23:00 Iodine tho
4:23:58 Nutrients tho (+ more B12 tho)
4:27:15 Calcium tho
4:28:08 Zinc tho
4:36:53 Choline tho
4:38:35 Taurine tho
4:39:45 Retinol tho (Vitamin A)
4:55:44 EPA & DHA tho
4:57:20 Selenium tho
4:59:52 Iron tho
5:07:38 Ancestors tho
5:08:40 “Water fasting for a year!?”
5:11:40 Moral obligation to stop contributing to animal agriculture
5:12:55 Vitamin C tho
5:19:22 Speculations on gut microbiome
5:26:04 Comments on the Ornish and Esselstyn studies
5:30:05 Another TMAO study
5:35:40 Kresser shifts his standards
5:38:29 Nutrient density tho
5:50:50 “Oh I have…”
5:51:20 Conclusion
Correction: For the nutrient density study, saturated fat, acted sugar, and sodium did not make it to the standard nutrient density score, it only counted toward the LIM indicator and not towards the nutrient density indicator. All other criticisms for the nutrient density score still stand.
Part 1:
youtube.com/watch?v=Q9mL7MqJjII
Discord Invite (all studies can be found here):
discord.gg/jgqKjUB
Ask yourself:
youtube.com/askyourself
Original Video:
youtube.com/watch?v=ULtqCBimr6U
Thanks to Meg for these timestamps:
0:24 Introduction
4:13 Response to Kahn’s comments
14:28 The confounding factors that were controlled for in the Epic Oxford Study and the Health Food Shoppers Study from part 1
21:00 Diet switching in the Epic Oxford / OVS studies
38:40 Isaac and Avi summarize the last 25 mins
39:18 Resuming the podcast
41:04 TMAO (Trimethylamine N-oxide) argument starts to unfold
42:54 The fibrosis of kidneys in relation to TMAO
46:21 Explaining what TMAO is and why it is a bad argument
54:10 Kahn pointing out Kresser’s inconsistency on epidemiological studies
59:13 Kresser’s TMAO graph
1:05:51 TMAO and the gut microbiome
1:07:15 Fasting TMAO levels
1:12:00 Kahn not addressing the study
1:19:00 Dioxins in fish
1:21:53 Old tho
1:24:00 There is still an ethical problem with eating fish
1:25:07 Kresser speculating on which diets change microbiome composition
1:28:16 High fasting TMAO levels are what is correlated with atherosclerosis
1:32:50 Debate advice on staying out of situations that make you look bad
1:33:41 Thoughts on nutritional reductionism
1:40:07 Kahn’s speculations
1:46:35 The Yazdekhasti paper
1:48:22 Cat studies meme
1:51:20 Fish makes diabetes tho
1:58:10 Final point addressing TMAO
2:13:32 Bad ethical arguments for veganism
2:15:44 Responding to the chat’s objections, and reading through and commenting on the l-carnitine study
2:34:22 Importance of the evidence hierarchy
2:51:11 Summary of Avi’s response to the l-carnitine study
2:55:20 Resuming the podcast
2:59:48 Kahn derails from TMAO to diabetes and general health as a result of fish consumption
3:04:06 Methionine tho
3:08:21 Glycine tho
3:08:53 Fish Consumption and Incidence of Diabetes Meta-analysis
3:18:20 Nutritional black box tho
3:21:05 Meat allergy lone star tick
3:23:25 Rogan’s bias?
3:27:57 Rogan’s interest in the lone star tick
3:28:48 Glyphosate tho
3:29:56 Statistics and astrological signs tho
3:37:18 Isaac summarises Kresser’s medical sophistry
3:38:47 Relative risk tho
3:39:40 Association between maternal gluten intake and type 1 diabetes in offspring (Gluten tho)
3:44:23 Assertions that there could be other confounding factors that were not controlled for in the studies
3:52:50 B12 tho
4:04:40 Humans can get B12 from dirt and water myth
4:06:46 Things that vegans need to stop saying
4:11:41 “Vegans living without supplementation are not living a healthy life”
4:13:10 Kahn demonstrates his simple B12 solution
4:15:49 “Diets do not need to be supplement free” (Natural tho)
4:19:00 Kahn demonstrates how easy supplementing is once more
4:23:00 Iodine tho
4:23:58 Nutrients tho (+ more B12 tho)
4:27:15 Calcium tho
4:28:08 Zinc tho
4:36:53 Choline tho
4:38:35 Taurine tho
4:39:45 Retinol tho (Vitamin A)
4:55:44 EPA & DHA tho
4:57:20 Selenium tho
4:59:52 Iron tho
5:07:38 Ancestors tho
5:08:40 “Water fasting for a year!?”
5:11:40 Moral obligation to stop contributing to animal agriculture
5:12:55 Vitamin C tho
5:19:22 Speculations on gut microbiome
5:26:04 Comments on the Ornish and Esselstyn studies
5:30:05 Another TMAO study
5:35:40 Kresser shifts his standards
5:38:29 Nutrient density tho
5:50:50 “Oh I have…”
5:51:20 Conclusion
Correction: For the nutrient density study, saturated fat, acted sugar, and sodium did not make it to the standard nutrient density score, it only counted toward the LIM indicator and not towards the nutrient density indicator. All other criticisms for the nutrient density score still stand.
