Continuous-time deconvolutional regression: A method for studying continuous dynamics in naturali... @MITCBMM
Continuous-time deconvolutional regression: A method for studying continuous dynamics in naturali...  @MITCBMM
Uploaded February 2022 | Updated September 2026, 2 weeks ago
[full title] Continuous-time deconvolutional regression: A method for studying continuous dynamics in naturalistic data

Cory Shain, MIT
Abstract: Naturalistic experiments are of growing interest to neuroscientists and cognitive scientists. Naturalistic data can be hard to analyze because critical events can occur at irregular intervals, and measured responses to those events can overlap and interact in complex ways. For example, words come quickly enough during naturalistic reading and listening that the brain responses to words likely overlap in time, and inherent variability in word durations can make these responses difficult to identify from data. In this tutorial, I will present continuous-time deconvolutional regression (CDR), a new approach to analyzing naturalistic time series. CDR uses machine learning to estimate impulse response functions from data, but, unlike established methods like finite impulse response modeling, these functions are defined in continuous time. CDR can therefore directly estimate event-related responses in a range of naturalistic experiment types, including fMRI, EEG/MEG, and behavioral measures. The tutorial will demonstrate how to define, fit, and evaluate CDR models, how to test hypotheses in the CDR framework, how to visualize patterns with CDR, and how CDR can be used to relax a range of assumptions about time series data. These steps can be run from the command line using an open-source Python library, with no need for users to write any code.

The sample data+models for the CDR tutorial available here: dropbox.com/sh/yz4l5745nxz8h7w/AACWgDwfKjhkXlK0L5eM-d25a?dl=0. The files data.zip and models.zip need to be downloaded and extracted.
CDR can be installed with either Anaconda or python+pip. To install with pip, run: pip install github.com/coryshain/cdr/archive/refs/tags/v0.5.3.tar.gz
Conda installation instructions are available in the readme at github.com/coryshain/cdr.
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Continuous-time deconvolutional regression: A method for studying continuous dynamics in naturali...

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