Uploaded October 2025 | Updated September 2026, 2 weeks ago
Tanay Tandon is the co-founder and CEO of Athelas / Commure, the AI operating system for healthcare.
Commure’s technology powers over 20 million appointments annually and processes more than $25 billion in claims volume, helping clinicians and health systems work faster, smarter, and spend more time on patient care.
In this fireside with YC’s Ankit Gupta, Tanay shares how he built one of the most ambitious companies in healthcare, what AI means for doctors and patients, and why the next decade of medicine will be defined by software.
Chapters:
00:00 – From Rejection Letters to YC Acceptance
02:30 – What Athelas and Commure Actually Do
05:33 – Building a Medical Device at 19
09:00 – Lessons from Clinical Trials and Early Healthcare Startups
16:39 – Pivoting from Hardware to Healthcare Software
21:24 – Fixing Physician Burnout with AI
27:14 – The Rise of Ambient Documentation
32:43 – Stripe for Healthcare: Rebuilding the Financial Layer
36:45 – Competing with Epic and Scaling Nationwide
45:41 – The Next Decade of Medicine
Tanay Tandon is the co-founder and CEO of Athelas / Commure, the AI operating system for healthcare.
Commure’s technology powers over 20 million appointments annually and processes more than $25 billion in claims volume, helping clinicians and health systems work faster, smarter, and spend more time on patient care.
In this fireside with YC’s Ankit Gupta, Tanay shares how he built one of the most ambitious companies in healthcare, what AI means for doctors and patients, and why the next decade of medicine will be defined by software.
Chapters:
00:00 – From Rejection Letters to YC Acceptance
02:30 – What Athelas and Commure Actually Do
05:33 – Building a Medical Device at 19
09:00 – Lessons from Clinical Trials and Early Healthcare Startups
16:39 – Pivoting from Hardware to Healthcare Software
21:24 – Fixing Physician Burnout with AI
27:14 – The Rise of Ambient Documentation
32:43 – Stripe for Healthcare: Rebuilding the Financial Layer
36:45 – Competing with Epic and Scaling Nationwide
45:41 – The Next Decade of Medicine
