Uploaded August 2026 | Updated September 2026, 1 week ago

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Today’s real-world case on Doctordle is from NEJM! A 91-year-old man develops progressive exertional dyspnea over 8 months with a 35-lb unintentional weight loss.

Watch one of NEJM Clinician editors, Clem, play today’s game!

Can you guess the diagnosis in five tries or less? Test yourself at http://doctordle.org.