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Metabolic Mind | Childhood Obesity at the Crossroads of Science and Social Justice @metabolicmind | Uploaded May 2023 | Updated October 2024, 40 minutes ago.
Harvard's Dr. David Ludwig addresses whether GLP-1 weight loss drugs like semaglutide, Wegovy & Ozempic should replace keto and low-carb diets for obesity, even in children. Or can low-carb diets complement drug treatments to reduce costs and long-term health risks and provide a path to life-long metabolic health?

Dr. Ludwig's new paper on the social justice implications of this issue is co-authored by Dr. Jens J. Holst, who has been credited with discovering the hormone GLP-1.

The GLP-1 medications semaglutide, Wegovy & Ozempic have taken the weight loss community by storm. They are even recommended for children and adolescents with obesity. But what are the long-term consequences of such widespread use, and why has the medical community seemingly abandoned dietary changes and behavioral support for medications and surgery? And what about the impact on long-term metabolic health and on questions of social justice?

Dr. David Ludwig is a Harvard researcher and endocrinologist. We discuss how the mechanisms of these medications are similar to those of low-carb diets and how Dr. Ludwig feels there's room for short-term use of medications to complement low-carb nutrition for weight loss and improved metabolic health.

A key question we ask ourselves at Metabolic Mind is what impact GLP-1 drugs will have on brain function. They do not have the benefit that ketogenic diets do of leading to producing ketones, an efficient fuel for the brain, which appears to be a key mechanism of action of keto in treating serious mental illness. More research is needed to address this important topic.

Experts featured in this video:

David Ludwig, MD PhD
https://www.hsph.harvard.edu/profile/david-s-ludwig/
Twitter:twitter.com/davidludwigmd

Jens Holst MD, DMSc
https://bmi.ku.dk/english/Staff/?pure=en/persons/174510

Paper referenced in this video:
Childhood Obesity at the Crossroads of Science and Social Justice
jamanetwork.com/journals/jama/fullarticle/2804576

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Learn more about metabolic psychiatry and find helpful resources at metabolicmind.org


About us:
Metabolic Mind™ is a nonprofit initiative incubated by Baszucki Group. Our mission is to provide education and resources in the emerging field of metabolic psychiatry, including ketogenic interventions for mental disorders.

Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

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Childhood Obesity at the Crossroads of Science and Social Justice @metabolicmind

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