Case Record of the MGH: Cardiac Imaging in a Patient with Chest Pain and Dyspnea @NEJMgroup

Uploaded March 2026 | Updated September 2026, 2 weeks ago

In a woman with chest pain, dyspnea, and syncope, point-of-care ultrasonography revealed a large pericardial effusion, and transesophageal echocardiography revealed mitral-valve abnormalities, shown in a video.

Read the full case details in “A 57-Year-Old Woman with Chest Pain, Dyspnea, and Syncope,” a Case Record of the Massachusetts General Hospital, at NEJM.org.

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Case Record of the MGH: Cardiac Imaging in a Patient with Chest Pain and Dyspnea

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$HFpEF Explained — Prevalence, New Advances, and How to Diagnose | NEJM This first episode of a three-part Double Take video miniseries on heart failure with preserved ejection fraction (HFpEF) from the New England Journal of Medicine discusses how HFpEF differs from heart failure with reduced ejection fraction, key risk factors, underlying causes, and the challenges of diagnosis. The cardiologists walk through the diagnostic evaluation, including use of the H2FPEF score to support clinical decision making. For further reading, the following articles, referenced in this video, are available at NEJM.org: Empagliflozin in Heart Failure with a Preserved Ejection Fraction (Anker et al., in the October 14, 2021, issue, https://www.nejm.org/doi/full/10.1056/NEJMoa2107038 ), Semaglutide in Patients with Heart Failure with Preserved Ejection Fraction and Obesity (Kosiborod et al., in the September 21, 2023, issue, https://www.nejm.org/doi/full/10.1056/NEJMoa2306963 ), Finerenone in Heart Failure with Mildly Reduced or Preserved Ejection Fraction (Solomon et al., in the October 24, 2024, issue, https://www.nejm.org/doi/10.1056/NEJMoa2407107 ), Heart Failure with Preserved Ejection Fraction (Cannata and McDonagh, in the January 9, 2025, issue, https://www.nejm.org/doi/full/10.1056/NEJMcp2305181 ), and Tirzepatide for Heart Failure with Preserved Ejection Fraction and Obesity (Packer et al., in the January 30, 2025, issue, https://www.nejm.org/doi/full/10.1056/NEJMoa2410027 ). Funding for this Double Take is provided by the Doris Duke Foundation, committed to building a creative, equitable, and sustainable future. #medicaleducation #clinicalmedicine #nejm The New England Journal of Medicine is the world’s leading general medical journal. Continuously published for over 200 years, the Journal publishes peer-reviewed research along with interactive clinical content for physicians, educators, and the global medical community at NEJM.org.$

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Case Record of the MGH: Cardiac Imaging in a Patient with Chest Pain and Dyspnea