Uploaded August 2026 | Updated September 2026, 2 weeks ago
Can GLP-1 medications like semaglutide and tirzepatide actually improve inflammatory skin diseases? Dermatologist Dr. Dray explores the emerging research connecting GLP-1 medications, weight loss, metabolic health, and inflammation, including what this could mean for psoriasis, psoriatic arthritis, and hidradenitis suppurativa (HS).
GLP-1 medications are best known for treating type 2 diabetes and obesity, but researchers are increasingly investigating their potential effects on inflammation. This video explains why adipose tissue can contribute to systemic inflammation, how GLP-1 signaling may influence inflammatory pathways, and whether improvements in skin disease can occur beyond the effects of weight loss.
Dr. Dray discusses the latest evidence, including the TOGETHER-PsO trial, which investigated tirzepatide in people with moderate-to-severe psoriasis and overweight or obesity, as well as emerging research on GLP-1 medications and hidradenitis suppurativa.
The video also covers:
• What GLP-1 medications are and how they work
• Semaglutide vs. tirzepatide
• Why obesity and inflammation are connected
• GLP-1 medications and psoriasis
• Tirzepatide and psoriasis clearance
• GLP-1 medications and psoriatic arthritis
• GLP-1 medications and hidradenitis suppurativa
• Whether GLP-1s have anti-inflammatory effects beyond weight loss
• Why metabolic health matters in inflammatory skin disease
• Whether everyone with psoriasis or HS should take a GLP-1
• Common GLP-1 side effects and risks
• Why GLP-1 medications require medical supervision
• What happens when GLP-1 medications are discontinued
• The potential future role of GLP-1 medications in dermatology
⏱️ TIMESTAMPS
0:00 Could GLP-1 medications help inflammatory skin disease?
1:03 What are GLP-1 medications?
1:47 Why would a weight-loss medication help a skin disease?
3:44 GLP-1s and psoriasis
5:33 What does this mean for psoriasis treatment?
6:34 GLP-1s and psoriatic arthritis
7:48 GLP-1s and hidradenitis suppurativa
10:43 Could the benefit be independent of weight loss?
12:26 Why does obesity matter so much in these diseases?
14:00 Should everyone with psoriasis or HS take a GLP-1?
14:30 What about side effects?
16:20 Start low and go slow
17:26 What happens if you stop?
17:44 Who should manage the GLP-1?
18:43 Where does this leave us?
RELATED VIDEOS
Can Skincare Fix Ozempic Face?
youtu.be/zURv_nMTUc0
Nutritional Deficiencies From GLP-1 Medications
youtu.be/SXjwBXIZtvQ
Ozempic Face & Aging Effects of GLP-1 Medications
youtu.be/E0V7jgubOfc
GLP-1s and Hair Loss
youtu.be/0VW43kd63zM
DISCLAIMER
This video is for educational and informational purposes only and is not a substitute for individualized medical advice, diagnosis, or treatment. GLP-1 medications are prescription medications with potential benefits, side effects, contraindications, and risks. Anyone considering treatment should discuss whether a GLP-1 medication is appropriate with a qualified healthcare professional.
Dr. Dray's discussion of emerging research on GLP-1 medications and inflammatory skin disease does not mean that these medications are currently established treatments for psoriasis, psoriatic arthritis, or hidradenitis suppurativa in every patient.
#GLP1 #Ozempic #Wegovy #Mounjaro #Zepbound #Semaglutide #Tirzepatide #Psoriasis #HidradenitisSuppurativa #PsoriaticArthritis #Dermatologist #SkinHealth #Inflammation
FTC: This video is not sponsored. Links are commissionable, meaning I may earn commission from purchases made through links.
💜Shop my Amazon store https://o.bttn.io/0BwiPWFIZLG
💜Follow me on liketoknowit https://www.liketoknow.it/drdrayzday
💜Social media
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Disclaimer: This video is not intended to provide diagnosis, treatment or medical advice. Content provided on this Youtube channel is for informational purposes only. Please consult with a physician or other healthcare professional regarding any medical or health related diagnosis or treatment options. Information on this Youtube channel should not be considered as a substitute for advice from a healthcare professional. The statements made about specific products throughout this video are not to diagnose, treat, cure or prevent disease.
Can GLP-1 medications like semaglutide and tirzepatide actually improve inflammatory skin diseases? Dermatologist Dr. Dray explores the emerging research connecting GLP-1 medications, weight loss, metabolic health, and inflammation, including what this could mean for psoriasis, psoriatic arthritis, and hidradenitis suppurativa (HS).
GLP-1 medications are best known for treating type 2 diabetes and obesity, but researchers are increasingly investigating their potential effects on inflammation. This video explains why adipose tissue can contribute to systemic inflammation, how GLP-1 signaling may influence inflammatory pathways, and whether improvements in skin disease can occur beyond the effects of weight loss.
Dr. Dray discusses the latest evidence, including the TOGETHER-PsO trial, which investigated tirzepatide in people with moderate-to-severe psoriasis and overweight or obesity, as well as emerging research on GLP-1 medications and hidradenitis suppurativa.
The video also covers:
• What GLP-1 medications are and how they work
• Semaglutide vs. tirzepatide
• Why obesity and inflammation are connected
• GLP-1 medications and psoriasis
• Tirzepatide and psoriasis clearance
• GLP-1 medications and psoriatic arthritis
• GLP-1 medications and hidradenitis suppurativa
• Whether GLP-1s have anti-inflammatory effects beyond weight loss
• Why metabolic health matters in inflammatory skin disease
• Whether everyone with psoriasis or HS should take a GLP-1
• Common GLP-1 side effects and risks
• Why GLP-1 medications require medical supervision
• What happens when GLP-1 medications are discontinued
• The potential future role of GLP-1 medications in dermatology
⏱️ TIMESTAMPS
0:00 Could GLP-1 medications help inflammatory skin disease?
1:03 What are GLP-1 medications?
1:47 Why would a weight-loss medication help a skin disease?
3:44 GLP-1s and psoriasis
5:33 What does this mean for psoriasis treatment?
6:34 GLP-1s and psoriatic arthritis
7:48 GLP-1s and hidradenitis suppurativa
10:43 Could the benefit be independent of weight loss?
12:26 Why does obesity matter so much in these diseases?
14:00 Should everyone with psoriasis or HS take a GLP-1?
14:30 What about side effects?
16:20 Start low and go slow
17:26 What happens if you stop?
17:44 Who should manage the GLP-1?
18:43 Where does this leave us?
RELATED VIDEOS
Can Skincare Fix Ozempic Face?
youtu.be/zURv_nMTUc0
Nutritional Deficiencies From GLP-1 Medications
youtu.be/SXjwBXIZtvQ
Ozempic Face & Aging Effects of GLP-1 Medications
youtu.be/E0V7jgubOfc
GLP-1s and Hair Loss
youtu.be/0VW43kd63zM
DISCLAIMER
This video is for educational and informational purposes only and is not a substitute for individualized medical advice, diagnosis, or treatment. GLP-1 medications are prescription medications with potential benefits, side effects, contraindications, and risks. Anyone considering treatment should discuss whether a GLP-1 medication is appropriate with a qualified healthcare professional.
Dr. Dray's discussion of emerging research on GLP-1 medications and inflammatory skin disease does not mean that these medications are currently established treatments for psoriasis, psoriatic arthritis, or hidradenitis suppurativa in every patient.
#GLP1 #Ozempic #Wegovy #Mounjaro #Zepbound #Semaglutide #Tirzepatide #Psoriasis #HidradenitisSuppurativa #PsoriaticArthritis #Dermatologist #SkinHealth #Inflammation
FTC: This video is not sponsored. Links are commissionable, meaning I may earn commission from purchases made through links.
💜Shop my Amazon store https://o.bttn.io/0BwiPWFIZLG
💜Follow me on liketoknowit https://www.liketoknow.it/drdrayzday
💜Social media
Instagram @drdrayzday
Pinterest pinterest.com/drdrayzday
Facebook @DrDrayzDay
Twitter: @drdrayzday
Tiktok: @drdrayzday
Disclaimer: This video is not intended to provide diagnosis, treatment or medical advice. Content provided on this Youtube channel is for informational purposes only. Please consult with a physician or other healthcare professional regarding any medical or health related diagnosis or treatment options. Information on this Youtube channel should not be considered as a substitute for advice from a healthcare professional. The statements made about specific products throughout this video are not to diagnose, treat, cure or prevent disease.
