The Sheekey Science Show | Can miRNAs be used as aging biomarkers? @TheSheekeyScienceShow | Uploaded December 2020 | Updated October 2024, 4 days ago.
What are miRNAs and can they be used as biomarkers for aging?



TIMESTAMPS;
Intro - 00:00
What are miRNAs - 00:58
How they change during aging - 03:40
Effective biomarker? - 06:56
NMN study and tissue specific biomarker? - 08:00

REFERENCES;
Fehlmann, T., Lehallier, B., Schaum, N. et al. Common diseases alter the physiological age-related blood microRNA profile. Nat Commun 11, 5958 (2020). [doi.org/10.1038/s41467-020-19665-1](doi.org/10.1038/s41467-020-19665-1)

Aging Cell. 2018 Feb;17(1):e12687. doi: 10.1111/acel.12687. Epub 2017 Oct 17. **Age-associated microRNA expression in human peripheral blood is associated with all-cause mortality and age-related traits**

NMN:

Geroscience. 2019 Aug;41(4):419-439. doi: 10.1007/s11357-019-00095-x. Epub 2019 Aug 28.

Icons in intro; "freepik.com/free-photos-vectors/background"Background vector created by freepik - freepik.com