Blood-brain barrier dysfunction in Pediatric Acute Neuropsychiatric Syndrome (PANS)  - Part One @Autism-org
Blood-brain barrier dysfunction in Pediatric Acute Neuropsychiatric Syndrome (PANS)  - Part One  @Autism-org
Uploaded June 2024 | Updated September 2026, 3 weeks ago
Learn research updates on blood-brain barrier dysfunction in Pediatric Acute Neuropsychiatric Syndrome (PANS) and Regulation.

Jennifer Frankovich, MD, provides research updates on blood-brain barrier dysfunction in Pediatric Acute Neuropsychiatric Syndrome (PANS).

NOTE: This is part one of a two-part talk - playback of Dr. Ayan Mondal’s presentation and Dr. Noor Hussein’s presentation will be available at a future date.

Free certificates of participation are available upon successful completion of a brief knowledge quiz at autism.org/blood-brain-barrier-dysfunction-in-pediatric-acute-neuropsychiatric-syndrome-pans-and-regulation

Dr. Frankovich is a Clinical Professor in the Department of Pediatrics, Division of Allergy, Immunology Rheumatology (AIR) at Stanford University/Lucile Packard Children’s Hospital (LPCH). Her clinical expertise is in systemic inflammatory and autoimmune diseases that co-occur with psychiatric symptoms. She completed her training in pediatrics, pediatric rheumatology, and clinical epidemiology at Stanford University/LPCH. She directs the Stanford Immune-Behavioral Health Program (2012- present) where she and her psychiatry/psychology collaborators have created a longitudinal clinical database and biorepository of patient and healthy control biospecimens. In addition to generating clinical data to better understand immune-behavioral health conditions, she is collaborating with basic science labs who aim to understand the immunological underpinnings of post-infectious neuropsychiatric conditions including PANS and related conditions.

In this webinar:
1:30 – PANS/PANDAS overview
3:10 – Underlying mechanisms
5:00 – Common symptoms
7:55 – PANS trajectories
9:35 – Basal Ganglia
13:12 – Antibodies and the blood-brain barrier
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Blood-brain barrier dysfunction in Pediatric Acute Neuropsychiatric Syndrome (PANS) - Part One

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