The ScienceVerse | Billions Wasted? The Dark Side of Alzheimer's Research @TheScienceVerse | Uploaded 1 month ago | Updated 8 hours ago
Video Author’s
Milan Sivakumar, M.D-UTSW School of Medicine 2027
In 1906, Alois Alzheimer first identified the disease that would later bear his name, characterized by abnormal protein buildups in the brain. Alzheimer's disease now affects millions and remains a leading cause of death in individuals over 65 in the U.S. Despite billions invested in research, ethical breaches like data fabrication have tainted some studies, raising concerns about the future of Alzheimer's research. This video explores the pathophysiology of Alzheimer's, focusing on amyloid-beta and tau proteins, and delves into the controversy surrounding the 2006 study on amyloid-beta 56. We discuss the implications of these findings on drug trials and the importance of exploring other mechanisms beyond amyloid buildup to develop effective treatments.
Sources:
https://canopy.uc.edu/default/news/detail?feed=uc_news&id=844a356d-2af1-5bc0-8412-68865d4f79ed
https://memory.georgetown.edu/news/allegations-of-fraud-in-alzheimers-disease-research-death-of-the-amyloid-hypothesis%EF%BF%BC/
https://memory.georgetown.edu/news/allegations-of-fraud-in-alzheimers-disease-research-death-of-the-amyloid-hypothesis%EF%BF%BC/
science.org/conte
nt/blog-post/faked-beta-amyloid-data-what-does-it-mean
ncbi.nlm.nih.gov/pmc/articles/PMC5576861
read.qxmd.com/read/38226975/aducanumab-anti-amyloid-immunotherapy-induces-sustained-microglial-and-immune-alterations
Music Credit:
Hopeless - Jimena Contreras
"I Am a Man Who Will Fight for Your Honor" by Chris Zabriskie is licensed under a Creative Commons Attribution 4.0 license. creativecommons.org/licenses/by/4.0
Source: http://chriszabriskie.com/honor
Artist: http://chriszabriskie.com
Stay tuned for more in-depth science videos!
Video Author’s
Milan Sivakumar, M.D-UTSW School of Medicine 2027
In 1906, Alois Alzheimer first identified the disease that would later bear his name, characterized by abnormal protein buildups in the brain. Alzheimer's disease now affects millions and remains a leading cause of death in individuals over 65 in the U.S. Despite billions invested in research, ethical breaches like data fabrication have tainted some studies, raising concerns about the future of Alzheimer's research. This video explores the pathophysiology of Alzheimer's, focusing on amyloid-beta and tau proteins, and delves into the controversy surrounding the 2006 study on amyloid-beta 56. We discuss the implications of these findings on drug trials and the importance of exploring other mechanisms beyond amyloid buildup to develop effective treatments.
Sources:
https://canopy.uc.edu/default/news/detail?feed=uc_news&id=844a356d-2af1-5bc0-8412-68865d4f79ed
https://memory.georgetown.edu/news/allegations-of-fraud-in-alzheimers-disease-research-death-of-the-amyloid-hypothesis%EF%BF%BC/
https://memory.georgetown.edu/news/allegations-of-fraud-in-alzheimers-disease-research-death-of-the-amyloid-hypothesis%EF%BF%BC/
science.org/conte
nt/blog-post/faked-beta-amyloid-data-what-does-it-mean
ncbi.nlm.nih.gov/pmc/articles/PMC5576861
read.qxmd.com/read/38226975/aducanumab-anti-amyloid-immunotherapy-induces-sustained-microglial-and-immune-alterations
Music Credit:
Hopeless - Jimena Contreras
"I Am a Man Who Will Fight for Your Honor" by Chris Zabriskie is licensed under a Creative Commons Attribution 4.0 license. creativecommons.org/licenses/by/4.0
Source: http://chriszabriskie.com/honor
Artist: http://chriszabriskie.com
Stay tuned for more in-depth science videos!
