BI 155 Luiz Pessoa: The Entangled Brain @braininspired
BI 155 Luiz Pessoa: The Entangled Brain  @braininspired
Uploaded December 2022 | Updated September 2026, 47 minutes ago
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Show notes: braininspired.co/podcast/155

Luiz Pessoa runs his Laboratory of Cognition and Emotion at the University of Maryland, College Park, where he studies how emotion and cognition interact. On this episode, we discuss many of the topics from his latest book, The Entangled Brain: How Perception, Cognition, and Emotion Are Woven Together, which is aimed at a general audience. The book argues we need to re-think how to study the brain. Traditionally, cognitive functions of the brain have been studied in a modular fashion: area X does function Y. However, modern research has revealed the brain is highly complex and carries out cognitive functions in a much more interactive and integrative fashion: a given cognitive function results from many areas and circuits temporarily coalescing (for similar ideas, see also BI 152 Michael L. Anderson: After Phrenology: Neural Reuse). Luiz and I discuss the implications of studying the brain from a complex systems perspective, why we need go beyond thinking about anatomy and instead think about functional organization, some of the brain's principles of organization, and a lot more.

0:00 - Intro
2:47 - The Entangled Brain
16:24 - How to think about complex systems
23:41 - Modularity thinking
28:16 - How to train one's mind to think complex
33:26 - Problem or principle?
44:22 - Complex behaviors
47:06 - Organization vs. structure
51:09 - Principles of organization: Massive Combinatorial Anatomical Connectivity
55:15 - Principles of organization: High Distributed Functional Connectivity
1:00:50 - Principles of organization: Networks as Functional Units
1:06:15 - Principles of Organization: Interactions via Cortical-Subcortical Loops
1:08:53 - Open and closed loops
1:16:43 - Principles of organization: Connectivity with the Body
1:21:28 - Consciousness
1:24:53 - Emotions
1:32:49 - Emottions and AI
1:39:47 - Emotion as a concept
1:43:25 - Complexity and functional organization in AI
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BI 155 Luiz Pessoa: The Entangled Brain

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